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Physiological Development of Retinal Synapses

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Cellular Communication During Ocular Development

Part of the book series: Cell and Developmental Biology of the Eye ((EYE))

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Abstract

Studies which have examined the development of ganglion cell receptive fields emphasize the contrasting maturation sequence of center vs. surround organization. Initially, ganglion cell responses are dominated by the center, whereas the surround activity is either absent or very weak (Bowe-Anders et al., 1975; Rusoff and Dubin, 1977; Masland, 1977). Center-surround antagonism increases with age as the surround mechanism gradually matures and eventually achieves adult characteristics. In the rabbit this period of receptive field development occurs between 8 and 30 days of age: by 30 days of age most cells have adult receptive field properties.

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References

  • Blanks, J.C., A. Adinolfi and R. Lolley. 1974. Synaptogenesis in the photoreceptor terminal of the mouse retina. J. Comp. Neurol.156: 81–93.

    Article  PubMed  CAS  Google Scholar 

  • Bowe-Anders, C., R.F. Miller and R.F. Dacheux. 1975. Developmental characteristics of receptive organization in the isolated retina eye-cup of the rabbit. Brain Res. 87: 61–65.

    Article  PubMed  CAS  Google Scholar 

  • Dacheux, R.F., T.E. Frumkes and R.F. Miller. 1979. Pathways and polarities of synaptic interactions in the inner retina of the mudpuppy: Synaptic blocking studies. Brain Res. 161: 1–12.

    Article  PubMed  CAS  Google Scholar 

  • Dacheux, R.F. and R.F. Miller. 1981a. An intracellular electrophysiological study of the ontogeny of functional synapses in the rabbit retina. I. Receptors, horizontal and bipolar cells. J. Comp. Neurol. 198: 301–326.

    Google Scholar 

  • Dacheux, R.F. and R.F. Miller. 1981b. An intracellular electrophysiological study of the ontogeny of functional synapses in the rabbit retina. II. Receptors, horizontal and bipolar cells. J. Comp. Neurol. 198: 327–334.

    Article  PubMed  CAS  Google Scholar 

  • DeMonasterio, F.M. 1978. Spectral interactions in horizontal and ganglion cells of the isolated and arterially perfused rabbit retina. Brain Res. 150: 239–258.

    Article  CAS  Google Scholar 

  • Kaneko, A. 1970. Physiological and morphological identification of horizontal, bipolar and amacrine cells in goldfish retina. J. Physiol. (Lond.) 207: 623–633.

    CAS  Google Scholar 

  • Masland, R.H. 1977. Maturation of function in developing rabbit retina. J. Comp. Neurol. 175: 275–286.

    Article  PubMed  CAS  Google Scholar 

  • McArdle, C.B., J.E. Dowling and R.H. Masland. 1977. Development of outer segments and synapses in the rabbit retina. J. Comp. Neurol. 175: 253–274.

    Article  PubMed  CAS  Google Scholar 

  • Miller, R.F. and R.F. Dacheux. 1973. Information processing in the retina: Importance of chloride ions. Science 181: 266–268.

    Article  PubMed  CAS  Google Scholar 

  • Miller, R.F. and R.F. Dacheux. 1976a. Synaptic organization and ionic basis of “on” and “off” channels in the mudpuppy retina. III. A model of ganglion cell receptive field organization based on chloride free experiments. J. Gen. Physiol. 67: 679–690.

    Article  PubMed  CAS  Google Scholar 

  • Miller, R.F. and R.F. Dacheux. 1976b. Dendritic and somatic spikes in mudpuppy amacrine cells: Identification and TTX sensitivity. Brain Res. 104: 157–162.

    Article  PubMed  CAS  Google Scholar 

  • Naka, K.I. 1976. Neuronal circuitry in the catfish retina. Invest. Ophthalmol. 15: 926–935.

    Google Scholar 

  • Nelson, R. 1977. Cat cones have rod input: A comparison of the response properties of cones and horizontal cell bodies in the retina of the cat. J. Comp. Neurol. 172: 109–136.

    Article  PubMed  CAS  Google Scholar 

  • Noell, W.K. 1958. Differentiation, metabolic organization and viability of the visual cell. Arch. Ophthalmol. 60: 702–733.

    CAS  Google Scholar 

  • Richter, A. and E.J. Simon. 1975. Properties of center hyperpolarizing, red-sensitive biopolar cells in the turtle retina. J. Physiol. (Lond.) 248: 317–334.

    CAS  Google Scholar 

  • Rusoff, A. and M. Dubin. 1977. Development of receptive field properties of retinal ganglion cells in kitten. J. Neurophysiol. 40: 1188–1198.

    PubMed  CAS  Google Scholar 

  • Steinberg, R.H. 1969. The rod after-effect in S-potentials from the cat retina. Vision Res. 9: 1345–1355.

    Article  PubMed  CAS  Google Scholar 

  • Werblin, F.S. 1977. Synaptic interactions mediating bipolar responses in the retina of the tiger salamander. In “Vertebrate Photoreception” (Barlow and Fatt, eds.) London: Academic Press, pp. 205–230.

    Google Scholar 

  • Werblin, F.S. and J.E. Dowling. 1969. Organization of the retina of the mudpuppy Necturus maculosus: II. Intracellular recording. J. Neurophysiol. 32: 339–355.

    PubMed  CAS  Google Scholar 

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© 1982 Springer-Verlag New York Inc.

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Dacheux, R.F. (1982). Physiological Development of Retinal Synapses. In: Sheffield, J.B., Hilfer, S.R. (eds) Cellular Communication During Ocular Development. Cell and Developmental Biology of the Eye. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5764-6_3

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  • DOI: https://doi.org/10.1007/978-1-4612-5764-6_3

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-5766-0

  • Online ISBN: 978-1-4612-5764-6

  • eBook Packages: Springer Book Archive

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