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Characterization and Isolation of Dopamine-Binding Proteins in Rat CNS by Gel Electrophoresis & Affinity Chromatography

  • Louise L. Hsu
  • Kayoko Moroi
  • Angelos E. Halaris
Part of the Experimental and Clinical Neuroscience book series (ECN)

Abstract

During the last decade, neurotransmitter receptors in the central nervous system have received considerable attention from investigators in search of unknown factors that may be involved in the etiology of various neurological and psychiatric disorders. In particular, dopamine (DA) receptors have been shown to be related to tardive dyskinesia (Baldessarini and Tarsey, 1980; Creese and Snyder, 1980 and Jeste and Wyatt, 1981), Parkinson’s disease (Lee et al., 1981 and Rinne, et al., 1981), Huntington’s Chorea (Login et al., 1982) and schizophrenia (Crow et al., 1978; Lee et al., 1978; Lee and Seeman, 1980; and Mackay et al., 1980).

Keywords

Dopamine Receptor Tardive Dyskinesia Corpus Striatum Synaptosomal Fraction Sodium Borate Buffer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Humana Press Inc. 1983

Authors and Affiliations

  • Louise L. Hsu
    • 1
  • Kayoko Moroi
    • 1
  • Angelos E. Halaris
    • 2
  1. 1.Department of Psychiatry and Behavioral SciencesThe University of Texas Medical BranchGalvestonUSA
  2. 2.Department of PsychiatryUCLA School of Medicine and Veterans Administration HospitalBrentwood, Los AngelesUSA

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