Abstract
Human Ia molecules have been isolated from the DR5 homozygous cell line Swei by alloantisera, and analyzed by 2-D gel electrophoresis, tryptic peptide mapping, and lectin affinity chromatography. Two distinct α chains and three distinct β chains have been identified. These chains associate to form molecules composed of α1β2, α1β3 and α2β1. The α1β2 + α1β3 molecules bear some oligosaccharide structures not found on the α2β1 molecule.
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Schwartz, B.D., Karr, R.W., Kannapell, C., Stein, J.A., Hahn, Y., Cowan, E.P. (1983). Three Distinct Human Ia Molecules Isolated from a DR5 Homozygous Lymphoblastoid Cell Line. In: Pierce, C.W., Cullen, S.E., Kapp, J.A., Schwartz, B.D., Shreffler, D.C. (eds) Ir Genes. Experimental Biology and Medicine, vol 4. Humana Press. https://doi.org/10.1007/978-1-4612-5633-5_25
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DOI: https://doi.org/10.1007/978-1-4612-5633-5_25
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