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Ir Genes pp 13-17 | Cite as

Murine T Cell-Specific IA Antigens: Helper T Lymphocytes Express a Unique I-A-Encoded Molecule

  • Colleen E. Hayes
  • Robert M. Whitcomb
  • David P. Krum
  • Karen K. Klyczek
  • Debra A. Hullett
Part of the Experimental Biology and Medicine book series (EBAM, volume 4)

Abstract

Genetic and environmental influences determine an animal’s capacity to respond immunologically to a foreign stimulus. The murine major histocompatibility complex (H-2) linked immune response (Ir) genes provide a model wherein the molecular basis for immune regulation can be examined (1). Cellular interactions, cell-mediated antiviral immunity, self-nonself discrimination, and immune suppression are H-2I region controlled traits (1).

Keywords

Keyhole Limpet Hemocyanin Specific Monoclonal Antibody Sepharose Column Antibody Synthesis Adoptive Transfer Experiment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Humana Press Inc. 1983

Authors and Affiliations

  • Colleen E. Hayes
    • 1
  • Robert M. Whitcomb
    • 1
  • David P. Krum
    • 1
  • Karen K. Klyczek
    • 1
  • Debra A. Hullett
    • 1
  1. 1.Department of Biochemistry, College of Agricultural and Life SciencesUniversity of WisconsinMadisonUSA

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