Evolution of Ribosomal Structure and Function

  • Odd Nygård
  • Peter Westermann


Ribosomes from all organisms have similar three-dimensional structures and functional domains. They are generally subdivided into two domains, each associated with a set of specific functions (Bernabeu and Lake 1982). Ribosomes contain a Translational Domain consisting of the apparatus for reading the message and an Exit Domain that is the site of emergence of the nascent protein chain and of membrane binding. The locations of these sites within the general scheme of ribosomal organization is shown in Figure 1.


Small Subunit Rough Endoplasmic Reticulum Exit Site Ribosomal Structure Peptidyl Transferase 
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Copyright information

© The Human Press Inc. 1983

Authors and Affiliations

  • Odd Nygård
    • 1
  • Peter Westermann
    • 2
  1. 1.The Wenner-Gren InstituteUniversity of StockholmStockholmSweden
  2. 2.Central Institute of Molecular BiologyAcademy of Sciences of GDRBerlin-BuchGermany

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