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Ribosomal Contributions to messenger RNA Directed Selection of transfer RNA

  • Odd Nygård
  • Peter Westermann
Chapter
  • 66 Downloads

Abstract

There exist mutated E.coli ribosomes which are more error prone than are wild type ribosomes (Gorini, 1971; Zimmerman et.al., 1971; Andersson et.al., 1982). There also exist ribosomal mutants which are more accurate than the wild type (Gorini & Kataja, 1964; Gorini, 1971). This pattern indicates that there exists an optimum choice of error levels in the bacterium. We wish to suggest that this optimum is a balance between the drawbacks of a too large fraction of faulty proteins on the one hand and the extra energetic costs of too low error frequencies on the other.

Keywords

Ternary Complex Guanine Nucleotide Standard Free Energy Nucleoside Triphosphate Peptide Bond Formation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Human Press Inc. 1983

Authors and Affiliations

  • Odd Nygård
    • 1
  • Peter Westermann
    • 2
  1. 1.The Wenner-Gren InstituteUniversity of StockholmStockholmSweden
  2. 2.Central Institute of Molecular BiologyAcademy of Sciences of GDRBerlin-BuchGermany

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