Skip to main content
SpringerLink
Log in

HPLC Sample Injection and Column Switching

  • Chapter
Liquid Chromatography in Environmental Analysis

Part of the book series: Contemporary Instrumentation and Analysis ((CIA))

Abstract

Snyder and Kirkland (1) and more recently Lawrence (2) have discussed a number of ways to inject samples into the liquid chromatograph. They both conclude that a valve is the best way to inject samples onto HPLC columns. This chapter will discuss injection and column switching exclusively by HPLC valves.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Snyder, L. R.; Kirkland, J. J. “Introduction to Modern Liquid Chromatography”, 2nd ed.; Wiley: New York, 1979.

    Google Scholar 

  2. Lawrence, J. F. “Organic Trace Analysis by Liquid Chromatography”; Academic Press: New York, 1981.

    Google Scholar 

  3. Kirkland, J. J.; Yau, W. W.; Stoklosa, H. J.; Dilks, C. H. J. Chromatogr. Sci. 1977, 15, 303.

    CAS  Google Scholar 

  4. Kucera, P. J. Chromatogr. 1980, 198, 93.

    Article  CAS  Google Scholar 

  5. Scott, R. P.W.; Simpson, C. F. Pittsburgh Conference, 1981, paper 756;

    Google Scholar 

  6. Scott, R. P.W.; Simpson, C. F. J. Chromatogr. Sci. 1982, 20, 62.

    CAS  Google Scholar 

  7. Ramin, J. A.; Stearns, S. D. U. S. Patent #4,022,065, May 10, 1977.

    Google Scholar 

  8. Harvey, M. C.; Stearns, S. D. Am. Lab. 1982, 14(5), 68.

    CAS  Google Scholar 

  9. Burns, D. A. Pharmac. Tech. Mar. 1981, 53.

    Google Scholar 

  10. Karger, B. L.; Martin, M.; Guiochon, G. Anal. Chem. 1974, 46, 1640.

    Article  CAS  Google Scholar 

  11. Kirkland, J. J. Analyst (London) 1974, 99, 859.

    Article  CAS  Google Scholar 

  12. Pinkerton, K. A. HRCCC 1981, 4, 33.

    Article  CAS  Google Scholar 

  13. Scott, R. P.W.; Kucera, P. J. Chromatogr. 1979, 169, 51.

    Article  CAS  Google Scholar 

  14. Ishii, D.; Asai, K.; Hibi, K.; Jonokuchi, T.; Nagaya, M. J. Chromatogr. 1977, 144, 157.

    Article  CAS  Google Scholar 

  15. Novotny, M. Anal. Chem. 1981, 53, 1308A.

    Article  Google Scholar 

  16. Takeuchi, T.; Ishii, D. HRCCC 1981, 4, 469.

    Article  CAS  Google Scholar 

  17. Rabel, F. M. J. Chromatogr. Sci. 1980, 18, 394.

    CAS  Google Scholar 

  18. Harvey, M. C.; Stearns, S. D.; Nelson, J. W. Pittsburgh Conference, 1982, paper 439, also Spectra-Physics Chromatography Review, 1983.

    Google Scholar 

  19. “Ten Port Multifunctional Sampling Valves,” Product Bullletin, Valco Instruments Co., Inc., P. O. Box 55603, Houston, Texas, 77255.

    Google Scholar 

  20. Huber, J. F.K.; Van Der Linden, R.; Ecker, E.; Oreans, M. J. Chromatogr. 1973, 83, 267.

    Article  CAS  Google Scholar 

  21. Suatoni, J. C.; Swab, R. E. J. Chromatogr. Sci. 1975, 13, 361.

    CAS  Google Scholar 

  22. Harvey, M. C.; Stearns, S. D. Am. Lab. 1981, 13(2), 151.

    CAS  Google Scholar 

  23. Brown, C. H. Am. Lab. 1980, 12(6), 40.

    CAS  Google Scholar 

  24. Kaiser, R. E.; Oelrich, E. “Optimization in HPLC”, Huthig: New York, 1981.

    Google Scholar 

  25. Harvey, M. C.; Stearns, S. D. Pittsburgh Conference 1981, paper 548.

    Google Scholar 

  26. Erni, F.; Keller, H. P.; Morin, C.; Schmitt, M. J. Chromatogr. 1981, 204, 65.

    Article  CAS  Google Scholar 

  27. Huber, J. F.K.; Fogy, I.; Fioresi, C. Chromatographia 1980, 13, 395.

    Article  Google Scholar 

  28. Johnson, E. L.; Gloor, R.; Majors, R. E. J. Chromatogr. 1978, 149, 571.

    Article  CAS  Google Scholar 

  29. Apffel, J. A.; Alfredson, T. V.; Majors, R. E. J. Chromatogr. 1981, 206, 43.

    Article  CAS  Google Scholar 

  30. Martin, M.; Verrillon, F.: Eon, C.; Guiochon, G. J. Chromatogr. 1976, 125, 17.

    Article  CAS  Google Scholar 

  31. Kucera, P.; Manus, G. J. Chromatogr. 1981, 219, 1.

    Article  CAS  Google Scholar 

  32. Poile, A. F. Chromatogr. Newslett. 1980, 8(3), 65.

    CAS  Google Scholar 

  33. Miller, R. L.; Ogan, K.; Poile, A. F. Am. Lab. 1981, 13(7), 52.

    CAS  Google Scholar 

  34. Wahlund, K. G.; Lund, U. J. Chromatogr. 1976, 122, 269.

    Article  CAS  Google Scholar 

  35. Varghese, S. L.; Holmes, K. D.; Martin, G. W. Pittsburgh Conference 1981, paper 798.

    Google Scholar 

  36. Keith, L. H. Environ. Sci Tech. 1981, 15, 156.

    Article  Google Scholar 

  37. Little, J. N.; Fallick, G. J. J. Chromatogr. 1975, 112, 389.

    Article  CAS  Google Scholar 

  38. Creed, C. J. Res./Dev. 1976, September, 40.

    Google Scholar 

  39. Natl. Bur. Stand. (US) Tech. Note, 1976, 889, 30.

    Google Scholar 

  40. Eisenbeiss, F.; Hein, H.; Joester, R.; Naundorf, G. Chemie-Technik 1977, 6, 227;

    CAS  Google Scholar 

  41. Eisenbeiss, F.; Hein, H.; Joester, R.; Naundorf, G. Chromatogr. Newslett. 1978, 6, 8.

    CAS  Google Scholar 

  42. Ogan, K.; Katz, E.; Slavin, W. J. Chromatogr. Sci. 1978, 16, 517.

    CAS  Google Scholar 

  43. Frei, R. W.; Intern. J. Environ. Anal. Chem. 1978, 5, 143.

    Article  CAS  Google Scholar 

  44. Frei, R. W.; Spectra-Physics Chromatography Review 1979, 5(2), 7.

    Google Scholar 

  45. Werkhoven-Goewie, C. E.; Brinkman, U. A.Th.; Frei, R. W. Anal. Chem. 1981, 53, 2072.

    Article  CAS  Google Scholar 

  46. Harvey, M. C. unreported studies carried out at Shell Development Co., Westhollow Research Center, Houston, Texas.

    Google Scholar 

  47. We are indebted to James H. Whitford, Valco Instruments Co., Inc. for this two valve application.

    Google Scholar 

  48. Cassidy, R. M.; Elchuk, S. J. Chromatogr. Sci. 1981, 19, 503.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Valco Instruments, Houston, Texas, USA

    Mack C. Harvey & Stanley D. Stearns

Authors
  1. Mack C. Harvey
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Stanley D. Stearns
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Health and Welfare Canada, Ottawa, Canada

    James F. Lawrence

Rights and permissions

Reprints and permissions

Copyright information

© 1984 The Humana Press Inc.

About this chapter

Cite this chapter

Harvey, M.C., Stearns, S.D. (1984). HPLC Sample Injection and Column Switching. In: Lawrence, J.F. (eds) Liquid Chromatography in Environmental Analysis. Contemporary Instrumentation and Analysis. Humana Press. https://doi.org/10.1007/978-1-4612-5306-8_7

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-5306-8_7

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-9778-9

  • Online ISBN: 978-1-4612-5306-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation