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Aging in the Food-restricted Rat: Body Temperature, Receptor Function, and Morphologic Changes in the Brain

  • Christopher D. West
  • Ladislav Volicer
  • Deborah W. Vaughan

Abstract

This investigation examined three different aspects of aging rats maintained on a food-restricted diet that prolonged life: body temperature in young and old adults, receptor sensitivity in young and old adults, and neuromorphologic changes in extreme old age. We were interested to see 1) whether lower body temperature was a factor in the longevity of food-restricted rats, 2) whether receptor function was one of the age-sensitive variables affected by food restriction, and 3) whether certain morphologic changes found in the brains of old humans and certain very old monkeys and dogs would be found in the brains of the oldest food-restricted rats.

Keywords

Food Restriction Restricted Diet Neuritic Plaque Intermittent Fasting Membranous Body 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York, Inc. 1984

Authors and Affiliations

  • Christopher D. West
  • Ladislav Volicer
  • Deborah W. Vaughan

There are no affiliations available

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