Abstract
Cell-surface receptors are noted for their high degree of specificity in their interactions with appropriate ligands. In receptor mediated drug delivery the drug is attached to or associated with a ligand which recognizes a specific receptor on the surface of a target cell. The ligand can be a component of a phospholipid vesicle, e.g. liposome, a lipoprotein particle or a chemical derivative of a macromolecule, small peptide or oligosaccharide (Fig. 1). After ingestion the active free drug is liberated by intracellular enzymes to exert its pharmacological effect.
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Shen, T.Y. (1985). Drug Delivery via Cell-Surface Receptors. In: Borchardt, R.T., Repta, A.J., Stella, V.J. (eds) Directed Drug Delivery. Experimental Biology and Medicine, vol 7. Humana Press. https://doi.org/10.1007/978-1-4612-5186-6_13
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DOI: https://doi.org/10.1007/978-1-4612-5186-6_13
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