Abstract
A coacervation technique for microencapsulation using Eudragit Retard polymers [poly(methyl methacrylates) substituted by quaternary ammonium groups] as wall material is described, based upon phase separation using a cold chloroform-cyclohexane mixture together with polyisobutylene as a stabilizer. The effect of various parameters on the nature and properties of the microcapsules of potassium dichromate and paracetamol has been studied, in particular the alteration in wall content and structure and release rate of contents. The microcapsules are discrete, their properties are reproducible, and various degrees of sustained release are obtained.
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References
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Benita, S., Donbrow, M., and Hoffman, A. (1981). Patent applied for.
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© 1984 The Humana Press Inc.
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Donbrow, M., Benita, S., Hoffman, A. (1984). Microencapsulation of Dichromate and Paracetamol with Eudragit Retard Polymers Using Phase Separation by Nonsolvent Addition. In: Chang, T.M.S. (eds) Microencapsulation and Artificial Cells. Humana Press. https://doi.org/10.1007/978-1-4612-5182-8_26
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DOI: https://doi.org/10.1007/978-1-4612-5182-8_26
Publisher Name: Humana Press
Print ISBN: 978-1-4612-9601-0
Online ISBN: 978-1-4612-5182-8
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