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Monoclonal Antibodies in Cancer pp 65–95Cite as

Human Chorionic Gonadotropin Detection with Monoclonal Antibodies

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Part of the book series: Contemporary Biomedicine ((CB,volume 6))

Abstract

Hormone production in cancer can result from the presence of transformed endocrine cells that continue to secrete or, as in the case of human chorionic gonadotropin, the hormone can also be considered an onco-developmental gene product and thus may be produced by many different types of tumors. The use of hormones as cancer markers has been previously reviewed (Sell and Wahren, 1982). This article will concentrate on hormone detection using monoclonal antibodies, particularly those aspects of monoclonal antibodies against human chorionic gonadotropin that differ from antisera.

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Authors and Affiliations

  1. Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, New York, USA

    Paul H. Ehrlich, Zeinab A. Moustafa & Alexander Krichevsky

  2. Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, New York, USA

    Ricardo Mesa-Tejada

  3. The Institute of Cancer Research, College of Physicians and Surgeons of Columbia University, New York, New York, USA

    Ricardo Mesa-Tejada

Authors
  1. Paul H. Ehrlich
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  2. Zeinab A. Moustafa
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  3. Alexander Krichevsky
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  4. Ricardo Mesa-Tejada
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Editors and Affiliations

  1. University of Texas Health Science Center, Houston, Texas, USA

    Stewart Sell

  2. Scripps Clinic and Research Foundation, La Jolla, California, USA

    Ralph A. Reisfeld

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Ehrlich, P.H., Moustafa, Z.A., Krichevsky, A., Mesa-Tejada, R. (1985). Human Chorionic Gonadotropin Detection with Monoclonal Antibodies. In: Sell, S., Reisfeld, R.A. (eds) Monoclonal Antibodies in Cancer. Contemporary Biomedicine, vol 6. Humana Press. https://doi.org/10.1007/978-1-4612-5176-7_4

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  • DOI: https://doi.org/10.1007/978-1-4612-5176-7_4

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