X-Ray Diffraction Analyses of Glycosaminoglycans
In a uniaxially oriented fiber of a glycosaminoglycan, the molecules are extended and have symmetrical (usually helical) secondary structures. The long axes of the polymers are more or less parallel. Frequently, the fibers are also polycrystalline with clumps of molecules incorporated into small crystallites, where they make orderly lateral interactions with one another. Although this organization is artificial, its details may help illuminate the state of glycosaminoglycan molecules in solutions and tissues.
KeywordsDermatan Sulfate Keratan Sulfate Sodium Hyaluronate Glycosaminoglycan Chain Heterotypic Interaction
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