Abstract
DNA methyltransferases (DNA methylases) transfer methyl groups from S-adenosylmethionine (AdoMet) to certain adenine or cytosine bases in polymeric DNA (see Chapter 2). In prokaryotes, most methylases are associated with endonucleases as part of restriction-modification systems (see Chapter 6) though there also exist the dam and dcm methylases, which do not have associated endonucleases. In eukaryotes, the only methyltransferases characterized are those from higher eukaryotes and from Chlamydomonas, which methylate cytosine bases in DNA.
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© 1985 Springer-Verlag New York Inc.
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Adams, R.L.P., Burdon, R.H. (1985). The Methylation Machinery: DNA Methyltransferases. In: Molecular Biology of DNA Methylation. Springer Series in Molecular Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5130-9_5
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DOI: https://doi.org/10.1007/978-1-4612-5130-9_5
Publisher Name: Springer, New York, NY
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