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Recent state of lindane metabolism. Part III.

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Residue Reviews

Part of the book series: Residue Reviews ((RECT,volume 94))

Abstract

After publication of part II of our review in 1979 (Residue Reviews 72, 71) knowledge about the mechanisms of the metabolism of lindane and the other hexachlorocyclohexane isomers increased rapidly. The identification of new, till now unknown metabolites recedes and the basic research on mechanism of several degradation steps increased. Nowadays more than 80 lindane metabolites of different chemical structure and relevance are known. Some more than 70 metabolites were found in warm-blooded animals. Fundamental detections of lindane metabolites are listed in Table I in chronological order. Until 1964 only 10, from 1965 to 1970 35, from 1971 to 1975 118, and from 1976 to 1980 238 identifications of metabolites (sometimes of the same metabolites) were reported. Main activities in finding out and identification of unknown metabolites took place in the 70th years.

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  1. Central Institute for Nutrition of the Academy of Sciences of the German Democratic Republic, 1505 Bergholz-Rehbrücke, Germany

    R. M. Macholz & M. Kujawa

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    Francis A. Gunther

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Macholz, R.M., Kujawa, M. (1985). Recent state of lindane metabolism. Part III.. In: Gunther, F.A. (eds) Residue Reviews. Residue Reviews, vol 94. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5104-0_4

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