Anesthesia for Patients with Valvular Heart Disease

  • Carol L. Lake


In patients with valvular heart disease, cardiovascular stability will depend on the determinants of cardiac output—namely, heart rate, preload, afterload, and myocardial contractility—as well as the cardiac rhythm and myocardial oxygen balance. In anesthetizing patients with valvular disease, the anesthesiologist must consider the pathophysiologic effects of the disease process, compensatory cardiovascular changes, and the effects of anesthetic agents and techniques on both processes. Compensatory mechanisms for the loss of forward stroke volume include:
  1. 1.

    Increased preload (Frank-Starling mechanism);

  2. 2.

    Ventricular hypertrophy; and

  3. 3.

    Increased sympathetic activity.



Mitral Valve Left Atrium Valve Replacement Aortic Stenosis Mitral Regurgitation 
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© Springer-Verlag New York Inc. 1985

Authors and Affiliations

  • Carol L. Lake
    • 1
  1. 1.University of Virginia Medical CenterCharlottesvilleUSA

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