Abstract
A high molecular weight ribonuclease (MW 80,000 daltons) from human milk (HMRNase) has been isolated and purified to homogeneity. Antiserum raised against this enzyme does not cross react with any of the human serum proteins, suggesting that the enzyme is synthesized in the mammary cells and secreted into the milk. The anti HMRNase antibody is expected to be a useful reagent for diagnostic and prognostic studies of human mammary neoplasia in view of the reverse correlation of the amount of ribonuclease present in human milk and mammary tumour incidence implicated in earlier studies (1).
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© 1985 The Humana Press Inc.
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Hemavathj, R., Das, M.R. (1985). Purification and Characterization of a High Molecular Weight Human Milk Ribonuclease: Its Potential Use for Diagnosis and Prognosis of Human Mammary Neoplasia. In: Gallo, R.C., Stehelin, D., Varnier, O.E. (eds) International Symposium: Retroviruses and Human Pathology. Experimental Biology and Medicine, vol 11. Humana Press. https://doi.org/10.1007/978-1-4612-5008-1_37
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DOI: https://doi.org/10.1007/978-1-4612-5008-1_37
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