Retroviruses in Neoplasia Yesterday, Today and Tomorrow

  • N. Oker-Blom
  • S. Pfeifer-Ohlsson
  • K. Alitalo
Part of the Experimental Biology and Medicine book series (EBAM, volume 11)

Abstract

Some advances in retrovirus research are summarized, with emphasis, on the correlation between oncogenes and cellular genes governing proliferation and differentiation. The significance of these recent findings for the understanding of neoplastic and normal developmental processes is briefly discussed.

Keywords

Tyrosine Leukemia Sarcoma Polypeptide Tated 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Alitalo, K., Bishop, J.M., Smith, D.H., Chen, E.Y., Colby, W.W. & Levinson, A.D. (1983) Proc. Natl. Acad. Sci. USA 80, 100–104.PubMedCrossRefGoogle Scholar
  2. 2.
    Alitalo, K., Ramsay, G., Bishop, J.M., Pfeifer-Ohlsson, S., Colby, W.W. & Levinson A.D., (1983) Nature 306, 274–277.PubMedCrossRefGoogle Scholar
  3. 3.
    Alitalo, K., Schawab, M., Lin, C.C., Varmus, H.E. & Bishop, M. (1983) Proc. Natl. Acad. Sci. USA 80, 1707–1711.PubMedCrossRefGoogle Scholar
  4. 4.
    Armelin, H.A., Armelin, M.C.S, Kelly, K., Stewart, T., Leder, P., Cochran, B.H. & Stiles, C.D. (1984) Nature 310, 655–660.PubMedCrossRefGoogle Scholar
  5. 5.
    Baltimore, D. (1970) Nature 226, 1209–1211.PubMedCrossRefGoogle Scholar
  6. 6.
    Beug, H., Hayman, M.J. & Graf, T. (1982) Cancer Surveys 1, 205–277.Google Scholar
  7. 7.
    Bishop, J.M. (1983) Ann. Rev. Biochem. 52, 301–354.PubMedCrossRefGoogle Scholar
  8. 8.
    Bishop, J.M. (1983) Cell 32, 1018–1020.PubMedCrossRefGoogle Scholar
  9. 9.
    Boveri, T. (1914) Zur Frage der Erstehung Maligner Tumoren. Fische Verlag, Jena.Google Scholar
  10. 10.
    Cairns, J. (1981) Nature 289, 353–357.PubMedCrossRefGoogle Scholar
  11. 11.
    Donner, P., Greiser-Wilke, I. & Moelling, J. (1982) Nature 296, 262–266.PubMedCrossRefGoogle Scholar
  12. 12.
    Doolittle, R.F., Hunkapiller, M.W., Hood, L.E., Devare, S.G., Robbins, K.C., Aronson, S.A. & Antoniades, H.N. (1983) Science 221, 275–277.PubMedCrossRefGoogle Scholar
  13. 13.
    Downward, J., Yarden, Y., Mayes, E., Scrace, G., Totty, N., Stockwell, P., Ullrich, A., Schelssinger, J. & Waterfield, M.D. (1984) Nature 307, 521–527.PubMedCrossRefGoogle Scholar
  14. 14.
    Duran-Reynals, F. (1950) Am. J. Med. 8, 490–511.PubMedCrossRefGoogle Scholar
  15. 15.
    Eisenman, R.N., Tachibana, C.Y., Abrams, H.D. & Hann, S.R. (1984) submitted.Google Scholar
  16. 16.
    Hayward, W.S., Neel, B.G. & Astrin, S.M. (1981) Nature 290, 475–480.PubMedCrossRefGoogle Scholar
  17. 17.
    Heldin, C.H. & Westermark, B. (1984) Cell 37, 9–20.PubMedCrossRefGoogle Scholar
  18. 18.
    Huebner, R.J., & Todaro, G.J. (1969) Proc. Natl. Acad. Sci. USA 54, 1087–1094.CrossRefGoogle Scholar
  19. 19.
    Kamata, T. & Feramisco, J. (1984) Nature 310, 147–149.PubMedCrossRefGoogle Scholar
  20. 20.
    Kelly K., Cochran, G.H., Stiles, C.D. & Leder, P. (1983) Cell 35, 603–610.PubMedCrossRefGoogle Scholar
  21. 21.
    Klein, G. (1981) Nature 294, 313–318.PubMedCrossRefGoogle Scholar
  22. 22.
    Klein, G. (1983) Cell 32, 311–315.PubMedCrossRefGoogle Scholar
  23. 23.
    Land, H., Parada, L.F. & Weinberg, R.A. (1983) Science 222, 771–778.PubMedCrossRefGoogle Scholar
  24. 24.
    McGrath, J.P., Capon, D.J., Goeddel, D.B. & Levinson, A.D. (1984) Nature 310, 644–649.PubMedCrossRefGoogle Scholar
  25. 25.
    Oker-Blom, N., Hortling, L., Kallio, A., Nurmiaiho, E.L. & Westermarck, H. (1978) J. Gen. Virol. 40, 623–633.PubMedCrossRefGoogle Scholar
  26. 26.
    Oker-Blom, N., Hortling, L., Kallio, A., Nurmiaiho, E.L. & Westermarck, H. (1978) J. Gen. Virol. 40, 623–633.PubMedCrossRefGoogle Scholar
  27. 27.
    Pfeifer, S. (1984) Intervirology 21, 121–133.CrossRefGoogle Scholar
  28. 28.
    Pfeifer, S., Kallio, A., Vaheri, A., Petterson, R. & Oker-Blom, N. (1980) Int. J. Cancer. 25, 235–242.PubMedCrossRefGoogle Scholar
  29. 29.
    Pfeifer, S., Petterson, R.K., Kallio, A., Oker-Blom, N. & Vaheri, A. (1981) J. Virol. 40, 533–540.PubMedGoogle Scholar
  30. 30.
    Pfeifer, S., Zabielski, J., Ohlsson, R., Frykberg, L., Knowles, J., Petterson, R., Oker-Blom, N., Philipson, L., Vaheri, A. & Vennstrom, B. (1983) J. Virol. 46, 347–354.PubMedGoogle Scholar
  31. 31.
    Poiesz, B.J., Ruscetti, F.W., Gazdar, A.F., Bunn, P.A., Minna, J.D. & Gallo, R.C. (1980) Proc. Natl. Acad. Sci. USA 77, 7415–7419.PubMedCrossRefGoogle Scholar
  32. 32.
    Rous, P. (1911) J. Exp. Med. 13, 379–384.Google Scholar
  33. 33.
    Siebenlist, U., Hennighausen, L., Battey, J. & Leder, P. (1984) Cell 37, 381–391.PubMedCrossRefGoogle Scholar
  34. 34.
    Spandidos, D.A. & Wilkie, NM. (1984) Nature 310, 469–475.PubMedCrossRefGoogle Scholar
  35. 35.
    Spector, D., Varmus, H.E. & Bishop, J.M. (1978) Proc. Natl. Acad. Sci. USA 75, 4102–4106.PubMedCrossRefGoogle Scholar
  36. 36.
    Stehelin, D., Varmus, H.E., Bishop, J.M. & Vogt, P.K. (1976) Nature 260, 170–173.PubMedCrossRefGoogle Scholar
  37. 37.
    Sutrate, P., Bonner, T.I., Rapp, U.R., Jansen, H.W., Patschinsky, T. & Bister, K. (1984) Nature 309, 85–88.CrossRefGoogle Scholar
  38. 38.
    Temin, H.M. & Mizutami, S. (1970) Nature 226, 1211–1213.PubMedCrossRefGoogle Scholar
  39. 39.
    Todaro, G.J., & Huebner, R.J. (1972) Proc. Natl. Acad. Sci. USA 69, 1009–1015.PubMedCrossRefGoogle Scholar
  40. 40.
    Waterfield, M.D., Scrace, T., Whittle, N., Strobant, P., Johnsson, A., Wasteson, A., Westermark, B., Heldin, G.H., Huang J.D. & Deuel T.F. (1983) Nature 304, 35–39.PubMedCrossRefGoogle Scholar
  41. 41.
    Westermark, B., Heldin, G.H., Ek, B., Johnsson, A., Mellstrom, K., Nister, M. & Wasteson, A. (1983) In Growth and Maturation Factors, 1, G. Guroff, ed. (New York. John Wiley and Sons.) pp. 73–115.Google Scholar
  42. 42.
    Winqvist, R., Saksela, K. & Alitalo, K. (1984) EMBO J., in pressGoogle Scholar

Copyright information

© The Humana Press Inc. 1985

Authors and Affiliations

  • N. Oker-Blom
    • 1
  • S. Pfeifer-Ohlsson
    • 2
  • K. Alitalo
    • 3
  1. 1.University of HelsinkiFinland
  2. 2.Department of MicrobiologyUniversity of UmeaSweden
  3. 3.Department of VirologyUniversity of HelsinkiFinland

Personalised recommendations