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Bovine Leukemia Virus, a Distinguished Member of the Human T Lymphotropic Viruses Family

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International Symposium: Retroviruses and Human Pathology

Abstract

The Bovine Leukemia Virus (BLV) has many structural and functional characteristics in common with Human T lymphotropic Viruses (HTLVs). The most striking feature of these retroviruses is the existence of a Long Open Reading frame (LOR) located at the 3’ side of the provirus between the right end of the 3’ side of env gene and the left end of the Long Terminal Repeat (LTR). It is believed that the LOR protein product is of critical importance in the induction process of the tumor phase of bovine leukemia.

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Burny, A. et al. (1985). Bovine Leukemia Virus, a Distinguished Member of the Human T Lymphotropic Viruses Family. In: Gallo, R.C., Stehelin, D., Varnier, O.E. (eds) International Symposium: Retroviruses and Human Pathology. Experimental Biology and Medicine, vol 11. Humana Press. https://doi.org/10.1007/978-1-4612-5008-1_17

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  • DOI: https://doi.org/10.1007/978-1-4612-5008-1_17

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-9396-5

  • Online ISBN: 978-1-4612-5008-1

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