Clinical Toxicology Pharmacokinetics of 13-Cis-Retinoic Acid Administered Chronically at Low Doses Expected for Cancer Chemoprevention Trials

  • David S. Alberts
  • Libby Edwards
  • Yei-Mei Peng
  • Ruth Serokman
  • Thomas P. Davis
  • Frank L. MeyskensJr.
Chapter
Part of the Experimental Biology and Medicine, Vol. 10 book series (EBAM, volume 10)

Abstract

This work was supported by research grants CA-27502 and CA-17094 from the National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20205. We would like to thank Dr. Thomas Moon for his excellent scientific advice and Susan Leigh for her outstanding dedication in the coordination of collection of biological samples.

Keywords

Cholesterol Fatigue Toxicity HPLC Lymphoma 

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Copyright information

© The Humana Press Inc. 1986

Authors and Affiliations

  • David S. Alberts
    • 1
  • Libby Edwards
    • 1
  • Yei-Mei Peng
    • 1
  • Ruth Serokman
    • 1
  • Thomas P. Davis
    • 1
  • Frank L. MeyskensJr.
    • 1
  1. 1.Sections of Hematology and Oncology and Dermatology, Department of Medicine, Department of Pharmacology, and the Cancer Center Arizona Health Sciences CenterTucsonUSA

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