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The Genes of the Murine T Cell Receptor

  • Chapter
Human T Cell Clones

Part of the book series: Experimental Biology and Medicine ((EBAM,volume 9))

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Abstract

T cells recognize antigen in a way fundamentally different from B cells. It has been known now for a decade (1–3) that the T cell receptor sees the antigen, not alone, but in association the major histocompatibility complex (MHC, H-2 in the mouse). As a general rule cytotoxic T (Tc) cells recognize antigen in association with Class I MHC molecules and helper T (Th) cells do so with Class II structures (4,5).

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Author information

Authors and Affiliations

  1. Department of Medical Microbiology, Fairchild Building, Stanford University School of Medicine, 94305, Stanford, CA, USA

    Nicholas R. J. Gascoigne, Yueh-hsiu Chien, Phillip Patten, Daniel M. Becker, Tullia Lindsten, Joshua Kavaler, Nadine E. Lee & Mark M. Davis

Authors
  1. Nicholas R. J. Gascoigne
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  2. Yueh-hsiu Chien
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  3. Phillip Patten
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  4. Daniel M. Becker
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  5. Tullia Lindsten
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  6. Joshua Kavaler
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  7. Nadine E. Lee
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  8. Mark M. Davis
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Editor information

Editors and Affiliations

  1. Imperial Cancer Research Fund, Tumour Immunology Unit, Department of Zoology, University College London, London, UK

    Marc Feldmann

  2. MRC Tuberculosis and Related Infections, Hammersmith Hosptial, London, UK

    Jonathan R. Lamb

  3. Tissue Bank, Naval Medical Research Institute, Bethesda, Maryland, USA

    James N. Woody

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© 1985 The Humana Press Inc.

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Gascoigne, N.R.J. et al. (1985). The Genes of the Murine T Cell Receptor. In: Feldmann, M., Lamb, J.R., Woody, J.N. (eds) Human T Cell Clones. Experimental Biology and Medicine, vol 9. Humana Press. https://doi.org/10.1007/978-1-4612-4998-6_3

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  • DOI: https://doi.org/10.1007/978-1-4612-4998-6_3

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-9391-0

  • Online ISBN: 978-1-4612-4998-6

  • eBook Packages: Springer Book Archive

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