Pharmacokinetics VII: Multiple Dosing from Absorptive Site

  • Ronald J. Tallarida
  • Rodney B. Murray


When a drug that is eliminated exponentially is administered via an absorptive route in equal doses D at equal time intervals T, the plasma concentration will fluctuate (Figure 32.1). The mean concentration approaches an upper limit.


Multiple Dose Clearance Rate Dose Interval Apparent Volume Equal Time Interval 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag New York Inc. 1987

Authors and Affiliations

  • Ronald J. Tallarida
    • 1
  • Rodney B. Murray
    • 2
  1. 1.Department of PharmacologyTemple University School of MedicinePhiladelphiaUSA
  2. 2.Department of PharmacologyBiosearch Inc.PhiladelphiaUSA

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