Abstract
A partial agonist is an agent that requires appreciable receptor occupancy in order to achieve an effect. By way of contrast, full agonists (or strong agonists) have a large spare receptor capacity, that is, these agents produce effects with just a small fraction of their receptors occupied.
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© 1987 Springer-Verlag New York Inc.
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Tallarida, R.J., Murray, R.B. (1987). Dissociation Constant II: Partial Agonists. In: Manual of Pharmacologic Calculations. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4974-0_14
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DOI: https://doi.org/10.1007/978-1-4612-4974-0_14
Publisher Name: Springer, New York, NY
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