Abstract
It is often desired to estimate the relative potencies of a number of drugs in a class that is based on some effect. For example, the agents might be vasodilators, or analgesics, or hormones, etc. Potency refers to the amount (mg, g, moles, etc.) of drug needed to produce a level of effect. Relative potency is the ratio of the amounts of each needed to produce the specified effect. Thus, one drug, the standard (S), is assigned unit potency and the second drug (U) is compared to that of S. The other drugs in the class are similarly compared.
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© 1987 Springer-Verlag New York Inc.
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Tallarida, R.J., Murray, R.B. (1987). Relative Potency I. In: Manual of Pharmacologic Calculations. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4974-0_11
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DOI: https://doi.org/10.1007/978-1-4612-4974-0_11
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4612-9380-4
Online ISBN: 978-1-4612-4974-0
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