Abstract
African swine fever (ASF) was first described in 1921 by Montgomery, who reported several disease outbreaks of domestic pigs in Kenya since 1910 with a mortality close to 100%. Montgomery recognized the viral nature of the disease, its likely transmission by wild swine which probably acted as virus carriers, and the lack of protection by passive immunization [1]. ASF is a menace to the pig population in the world because there is no vaccine, the virus multiplies in ticks and mutates easily, and different virus isolates can produce diseases with different clinical forms or no disease at all. The control and eradication of ASF require rapid diagnosis, drastic slaughter, and quarantine.
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References
Montgomery RE (1921) On a form of swine fever occurring in British East Africa (Kenya Colony) J Comp Pathol 34: 159–191, 243–262
Carrascosa JL, Carazo JM, Carrascosa AL, García N, Santisteban A, Viñuela E (1984) General morphology and capsid fine structure of African swine fever virus particles. Virology 132: 160–172
Carrascosa, AL, Santarén JF, Viñuela, E (1982) Production and titration of African swine fever virus in porcine alveolar macrophages. J Virol Methods 3: 303–310
Sanz A, García-Barreno B, Nogal ML, Viñuela E, Enjuanes L (1985) Monoclonal antibodies specific for African swine fever virus proteins. J Virol 54: 199–206
Carrascosa JL, González P, Carrascosa, AL, García-Barreno B, Enjuanes L, Viñuela E (1986) Localization of structural proteins in African swine fever virus particles by immunoelectron microscopy. J Virol 58: 377–384
Sogo JM, Almendral JM, Talavera A, Viñuela E (1984) Terminal and internal inverted repetitions in African swine fever virus DNA. Virology 133: 271–275
Baroudy BM, Venkatesan S, Moss B (1981) Incompletely base-paired flip-flop terminal loops link the two DNA strands of the vaccinia virus genome into one uninterrupted polynucleotide chain. Cell 28: 315–324
González A, Almendral JM, Talavera A, Viñuela E. 1986 (to be published)
Kuznar J, Salas ML, Vinñuela E (1980) DNA-dependent RNA polymerase in African swine fever virus. Virology 101: 169–175.
Salas ML, Kuznar J, Viñuela E (1981) Polyadenylation, methylation and capping of the RNA synthesized in vitro by African swine fever virus. Virology 113: 484–491
Salas ML, Kuznar J, Viñuela E (1983) Effect of rifamycin derivatives and coumermycin Al on in vitro RNA synthesis by African swine fever virus. Arch Virol 77: 77–80
Salas ML, Rey J, Almendral JM, Viñuela E (1986) (to be published)
Salas J, Salas ML, Viñuela E (1986) (to be published)
Viñuela E (1985) African swine fever virus. Curr Top Microbiol Immunol 116: 151–170
Colgrove G, Haelterman EO, Coggins L (1969) Pathogenesis of African swine fever virus in young pigs. Am J Vet Res 30: 1343–1359
Casal I, Enjuanes L, Viñuela E (1984) Porcine leukocyte cellular subsets sensitive to African swine fever virus in vitro. J Virol 52: 37–46
Mebus CA, McVicar JW, Dardiri AH (1981) Comparison of the pathology of high and low virulence African swine fever viral infections. CEC/FAO Expert Consultation on African swine fever virus, pp 23–25
Maurer FD, Griesemer RA, Jones TC (1958) The pathology of African swine fever—a comparison with hog cholera. Am J Vet Res 19: 517–539
Edwards JF, Dodds WJ, Slauson DO (1984) Coagulation changes in African swine fever virus infection. Am J Vet Res 45: 2414–2420
Edwards JF, Dodds WJ, Slauson DO (1985) Megakaryocytic infection and thrombocytopenia in African swine fever. Vet Pathol 22: 171–176
DeBoer CJ (1967) Studies to determine neutralizing antibody in sera from animals recovered from African swine fever and laboratory animals inoculated with African virus with adjuvants. Arch Ges Virusforsch 20: 164–179
Stone SS, Hess WR (1965) Separation of virus and soluble non-infectious antigens in ASFV by isoelectric precipitation. Virology 26: 622–629
Vigario JD, Terrinha AM, Moura Nunes JF (1974) Antigenic relationships among strains of African swine fever virus. Arch Ges Virusforsch 45: 272–277
Norley SG, Wardley RC (1982) Complement-mediated lysis of African swine fever virus-infected cells. Immunology 46: 75–82
Blasco R, Agüero M, Almendral JM, Viñuela E. (1986) (to be published)
García-Barreno B, Sanz A, Nogal ML, Viñuela E, Enjuanes E (1986) Monoclonal antibodies of African swine fever virus: Antigenic differences among field virus isolates and viruses passaged in cell culture. J. Virol 58: 385–392
Almendral JM, Blasco R, Viñuela E. (1986) (to be published)
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Viñuela, E. (1986). African Swine Fever Virus. In: Notkins, A.L., Oldstone, M.B.A. (eds) Concepts in Viral Pathogenesis II. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4958-0_28
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DOI: https://doi.org/10.1007/978-1-4612-4958-0_28
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