Ribosomal Proteins Tune Rate and Accuracy in Translation
Growing bacteria use a significant fraction of their investments in phosphodiester bonds and peptide bonds for the translation apparatus (Maaløe, 1979; Ingraham et al., 1983). These major investments in ribosomes and other proteins directly involved in translation appear to guarantee a fast growth rate under varying conditions (Maaløe, 1979; Ingraham et al., 1983). In spite of the impressive size of the ribosomal particle in Escherichia coli (Maaløe, 1979) and in spite of its occurrence in very high copy-numbers (Neidhardt et al., 1977), its role in gene expression somehow does not seem to correspond to its complexity.
KeywordsHydrolysis Codon Polypeptide Streptomycin Nucleoside
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