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How Do Protein L18 and 5S RNA Interact?

  • J. Christiansen
  • R. A. Garrett
Part of the Springer Series in Molecular Biology book series (SSMOL)

Abstract

The complex of 5S RNA and proteins L18 and L25 from Escherichia coli has proved useful for studying both the chemistry of protein-RNA interactions and for examining cooperative assembly effects within ribosomes (reviewed by Garrett et al. 1981, 1984). It has the following advantages over most other protein-RNA complexes for such seminal studies: Both RNA and proteins are available in large quantities; the RNA is relatively small and homogeneous; the RNA secondary structure has been determined both experimentally and by comparing sequences to detect coordinated base changes; and the proteins are small and of known sequence. The current disadvantage is that insufficient protein sequences are available for localizing conserved amino acids or peptide sequences.

Keywords

HB101 Cell Carboxamide Group Central Protuberance rrnB Operon 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1986

Authors and Affiliations

  • J. Christiansen
  • R. A. Garrett

There are no affiliations available

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