Abstract
The application of neutron scatter and diffraction techniques to structural studies of the nucleosome and of chromatin provides a striking example of the interface of modern physics and the life sciences. The structure and function of the eukaryotic chromosome is a major problem in molecular cell biology. One approach toward an understanding of the functions of such a complex system is to determine (i) the structure of the repeating chromatin subunit, the nucleosome, (ii) the arrangements of nucleosomes in the different orders of chromatin structure, and (iii) how these structural parameters change in response to the functional requirements of cells, i.e., to approach function through an understanding of structure.
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Bradbury, E.M., Baldwin, J.P. (1986). Neutron Scatter and Diffraction Techniques Applied to Nucleosome and Chromatin Structure. In: Nicolini, C. (eds) Bioscience at the Physical Science Frontier. Humana Press. https://doi.org/10.1007/978-1-4612-4834-7_4
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DOI: https://doi.org/10.1007/978-1-4612-4834-7_4
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