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Abstract

Had this essay been written before the conference, as it should have, it would probably have started with a general statement lamenting how few insect neuropeptides were actually sequenced. Fortunately this sentiment is no longer justified. We are entering a period of rapid proliferation of information on the primary structures of insect neuropeptides. An example of the increased pace of peptide analysis was provided in this meeting by the remarkable presentation of J. Cook and G.M. Holman. In proposing primary structures for several new myotropic peptides, at a single stroke these authors have at least doubled the number of structured insect peptides. Perhaps the single most important factor in facilitating this advance is the application of gas phase sequencing, a highly sensitive modification of Edman sequencing which can yield primary structures from as little as 10 pmoles of pure peptide.

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O’Shea, M. (1986). Insect Neuropeptides - Pure and Applied. In: Bořkovec, A.B., Gelman, D.B. (eds) Insect Neurochemistry and Neurophysiology · 1986. Experimental and Clinical Neuroscience. Humana Press. https://doi.org/10.1007/978-1-4612-4832-3_1

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  • DOI: https://doi.org/10.1007/978-1-4612-4832-3_1

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-9181-7

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