Abstract
Hematopoiesis is the process by which a pluripotent stem cell gives rise to the formed elements (recognizable differentiated cells) of the blood. These include red cells, platelets, lymphocytes, and cells of the granulocyte monocyte series (neutrophils, eosinophils, basophils, and monocyte-macrophages). The cellular biology and biochemistry of hematopoiesis have been intensively studied because the hematopoietic system is of fundamental scientific and clinical importance. As a biological phenomenon, hematopoiesis represents the most striking and readily examined example of differentiation by a single parent stem cell along several alternate cellular pathways. At the clinical level, hematopoiesis represents the means by which the body is supplied with cells needed for oxygen transport, infection resistance, and hemostasis.
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Benz, E.J. et al. (1987). Studies of Gene Expression During Granulocyte Maturation. In: Aarbakke, J., Chiang, P.K., Koeffler, H.P. (eds) Tumor Cell Differentiation. Experimental Biology and Medicine, vol 17. Humana Press. https://doi.org/10.1007/978-1-4612-4594-0_6
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DOI: https://doi.org/10.1007/978-1-4612-4594-0_6
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