Induction of Nonspecific Suppressor Cells by Different Epstein-Barr Virus Antigens

  • Syam K. Sundar
  • José Menezes
Part of the Experimental Biology and Medicine book series (EBAM, volume 15)

Abstract

We have examined in vitro the interaction of different Epstein-Barr virus (EBV) and other unrelated antigens and observed that non-specific suppressor T (Ts) cells can be generated under the following conditions: simultaneous presence of the antigen-specific Ts cell-inducing antigen and other unrelated (or multiple) antigens to which the test lymphocytes have been sensitized. Such a phenomenon may be responsible for inducing nonspecific Ts cells in vivo (e.g. infections and malignancies).

Keywords

Dine 

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Copyright information

© The Humana Press Inc. 1987

Authors and Affiliations

  • Syam K. Sundar
    • 1
  • José Menezes
    • 1
  1. 1.Laboratory of ImmunovirologyUniversity of Montreal and Ste-Justine HospitalMontrealCanada

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