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A Nude-Mouse-Grown NPC Tumor Produces Interleukin-1

  • P. Busson
  • K. Braham
  • G. Ganem
  • F. Thomas
  • M. Lipinski
  • D. Grausz
  • H. Wakasugi
  • T. Tursz
Part of the Experimental Biology and Medicine book series (EBAM, volume 15)

Abstract

IL-1 is the term currently accepted for a cytokine which has a variety of important pleomorphic functions in immuno-regulation and inflammation (1). It plays a central role in T cell activation, mainly through induction of IL-2 secretion by activated T cells.

Keywords

Autocrine Growth Factor Malignant Epithelial Cell Crude Supernatant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References and Notes

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    We thank Dr T. Kasahara (Jichi Medical school, Japan) for generous gift of anti-IL-1 polyclonal serum, Otsuka Pharmaceutical (Tokoshima, Japan) for generous gift of IL-1 cDNA probe, and anti IL-1 polyclonal serum, Dainippon Pharmaceutical (Osaka, Japan) for IL-1 cDNA probe, and Dr C. Dinarello (Tufts University, U.S.A.) for anti human IL-1 polyclonal serum. P. Busson was the recipient of a grant from Institut Gustave-Roussy, Villejuif, France. This work was partially supported by a grant form the Centre National de la Recherche Scientifique (CNRS), Paris, France (Grant No 95–75–17, ATP oncogenes).Google Scholar

Copyright information

© The Humana Press Inc. 1987

Authors and Affiliations

  • P. Busson
    • 1
  • K. Braham
    • 1
  • G. Ganem
    • 1
  • F. Thomas
    • 1
  • M. Lipinski
    • 1
  • D. Grausz
    • 1
  • H. Wakasugi
    • 1
  • T. Tursz
    • 1
  1. 1.Laboratoire D’Immuno-Biologie des TumeursInstitut Gustave-RoussyVillejuif CedexFrance

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