Abstract
In EBV-immortalized B-lymphocytes, the host cells are latently infected and only rarely undergo productive infection. To identify those factors that cause the switch from the latent to productive state, we are studying the regulation of the different classes of EBV promoters. We have constructed Plasmids which place the suspected promoter regions of five different EBV genes into the vector pCAT3M (1), which contains the bacterial chloramphenicol acetyl transferase (CAT) gene but no added eucaryotic promoter element.
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References
L. Laimons, P. Gruss, R. Pozzatti, and G. Khoury. J. Virology 49:183 (1984).
J. Sample, M. Hummel, D. Braun, M. Birkenbach, and E. Kieff. Proc. Natl. Acad. Sci. USA 83:5096 (1986).
G. Hudson, P. Farrell, and B. Barrell. J. Virology 53:528 (1985).
F. Graham and A. Vandererb. Virology 52:456 (1973).
J.H. McCutchan and J.S. Pagano. J. Natn. Cancer Inst. 41:351 (1965).
C. Gorman, G. Merlino, M. Willingham, I. Pastan, and B. Howard. Proc. Natl. Acad. Sci. USA 79:6777 (1982).
D. Reisman and B. Sugden. Mol. Cell. Biol. 6:3838 (1986).
P. Lieberman, P. O’Hare, G. Hayward, and D. Hayward. J. Virology 60: 140 (1986).
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© 1987 The Humana Press Inc.
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Kenney, S., Lin, J.C., Pagano, J.S. (1987). Regulation of EBV Promoters. In: Levine, P.H., Ablashi, D.V., Nonoyama, M., Pearson, G.R., Glaser, R. (eds) Epstein-Barr Virus and Human Disease. Experimental Biology and Medicine, vol 15. Humana Press. https://doi.org/10.1007/978-1-4612-4590-2_36
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DOI: https://doi.org/10.1007/978-1-4612-4590-2_36
Publisher Name: Humana Press
Print ISBN: 978-1-4612-8940-1
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