Skip to main content
SpringerLink
Log in

Dietary Simple Sugars Increase the Severity of Copper Deficiency in Experimental Animals

  • Chapter
Biology of Copper Complexes

Part of the book series: Experimental Biology and Medicine ((EBAM,volume 16))

  • 123 Accesses

Abstract

It is well established that diets consumed by subjects living in industrialized societies including the USA contain relatively high levels of simple sugars (1) but marginal amounts of copper (2). The feeding of simple sugars such as sucrose and fructose as compared to starch, to humans and experimental animals, produces undesirable changes in blood risk factor metabolites associated with heart disease (3). Low copper intake has a similar effect on these indices (4,5). Does sucrose feeding in combination with copper deficiency have an additive effect that is greater than the effect of either of these constituents alone? The purpose of our preliminary studies was to determine if diet composition can influence the severity of copper deficiency. Specifically, can a certain dietary component such as carbohydrate magnify or depress the deficiency.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Woteki, CE., Welsh, S.O., Raper, W., Manstom, R.M. In: Reiser S., ed. Metabolic effects of utilizable carbohydrates. New York, NY, Mancel Dekker 1982, p. 1.

    Google Scholar 

  2. Klevay, L.M. Ann. NY Acad. Sci. 1980, 355, 140.

    Article  PubMed  CAS  Google Scholar 

  3. Reiser, S. Nutr. & Health 1985, 3, 203.

    CAS  Google Scholar 

  4. Allan, K.G.D., Klevay, L.M. Atherosclerosis 1978, 29, 81.

    Article  Google Scholar 

  5. Klevay, L.M. Biol. Trace. Elem. Res. 1983, 5, 245.

    Article  CAS  Google Scholar 

  6. Fields, M., Ferretti, R.J., Smith, J.C., and Reiser, S. J. Nutr. 1983, 113, 1335.

    PubMed  CAS  Google Scholar 

  7. Reiser, S. In: Rechcigl Jr. M., ed. CRC Handbook Series in Nutrition and Food. Section E: Nutritional Disorders. West Palm Beach, FL: CRC Press, 1978, p. 409.

    Google Scholar 

  8. Cohen, A.M., Teitelbaum, A., Briller, S., Yanko, L., Rosemann, E., Shafrir, E. In: Sepple, H., McNutt, K., eds. Sugars in Nutrition. New York, NY: Academic Press, 1974, p. 483.

    Google Scholar 

  9. Pfeiffer, E.F. In: Greten, H., Levine, R., Pfeiffer, E.F., Renold, A.E., eds. Lipid metabolism, obesity and diabetes mellitus; impact upon athersclerosis. Stuttgart, Germany: Georg Thieme Publishers 1974, p. 143.

    Google Scholar 

  10. Laube, H., Wojcikowski, C, Schatz, H., Pfeiffer, E.F. Horm. Met. Res. 1978, 10, 192.

    Article  CAS  Google Scholar 

  11. Hallfirsch, J., Lazar, F., Jorgensen, C. Reiser, S. Am. J. Clin. Nutr. 1979, 32, 787.

    Google Scholar 

  12. Vrana, A. Kazdova, L. Life Science. 1970, 9, 257.

    Article  CAS  Google Scholar 

  13. Reiser, S., Hallfirsch, J. J. Nutr. 1977, 107, 147.

    PubMed  CAS  Google Scholar 

  14. Cohen, A.M., Tetelbaum, A., Rosenman, E. Metabolism. 1977, 25, 17.

    Article  Google Scholar 

  15. Blakely, S.R., Hallfrisch, J., Reiser, S., Prather, E.S. J. Nutr. 1981, 111, 307.

    PubMed  CAS  Google Scholar 

  16. Reiser, S., Ferretti, R.J., Fields, M., Smith, J.C., Role of dietary fructose in the enhancement of mortality and biochemical changes associated with copper deficiency in rats. Am. J. Clin. Nutr. 1983, 38, 214.

    PubMed  CAS  Google Scholar 

  17. Fields, M., Ferretti, R.J., Reiser, S., Smith, J.C. Proc. Soc. Expt. Biol & Med. 1984, 175, 530.

    CAS  Google Scholar 

  18. Fields, M., Ferretti, R.J., Smith, J.C., Reiser, S. Am. J. Clin. Nutr. 1984, 39, 289.

    PubMed  CAS  Google Scholar 

  19. Fields, M., Reiser, S., Smith J.C. Nutr. Rep. Int. 1983, 28, 165.

    Google Scholar 

  20. Fields, M., Ferretti, R.J., Smith, J.C, Reiser, S. J. Nutr. 1984, 114, 393.

    PubMed  CAS  Google Scholar 

  21. Fields, M., Ferretti, R.J., Smith, J.C, Reiser, S. Biol. Trace. Elem. Res. 1984, 6, 379.

    Article  CAS  Google Scholar 

  22. Fields, M., Michaelis, O.E.IV, Hallfrisch, J., Reiser, S., Smith, J.C. Nutr. Rep. Int. 1983, 28, 123.

    CAS  Google Scholar 

  23. Fields, M., Ferretti, R.J., Judge, J.M., Smith, J.C, Reiser, S. Proc. Soc. Exp. Biol. & Med. 1985, 178, 362.

    CAS  Google Scholar 

  24. Davis, P.S., Delier, D.J. Aust. Ann. Med. 1967, 16, 70.

    PubMed  CAS  Google Scholar 

  25. Fields, M., Craft, N., Lewis, C, Holbrook, J., Rose, A., Reiser, S. Smith, J.C. J. Nutr. 1986, 116, in press.

    Google Scholar 

  26. Fields, M., Holbrook, J., Scholfield, D., Smith, J.C., Reiser, S. J. Nutr. 1986, 116, 625.

    PubMed  CAS  Google Scholar 

  27. Holbrook, J., Fields, M., Smith, J.C, Reiser, S. J. Nutr. 1986, 116, 831.

    PubMed  CAS  Google Scholar 

  28. Fields, M., Lewis, CC, Rose, A., Smith, J.C, Reiser, S. Biol. Trace. Elem. Res. 1986, 10,(3) in press.

    Google Scholar 

  29. Steele, N., Richards, M., Darcey, S., Fields, M., Smith, J.C, Reiser, S. Fed. Proc. 1986, 45, 357 (abstact).

    Google Scholar 

  30. Ono, K., Steele, N., Richards, M., Darcey, S., Fields, M., Scholfield, D., Smith, J.C, Reiser, S. Fed. Proc. 1986, 45, 357. (abstract)

    Google Scholar 

  31. Reiser, S., Smith, J.C, Mertz, W., Holbrook, J.T. Scholfield, D., Powel, A.S., Canfield, W.K., Canary, J.J. Am. J. Clin. Nutr. 1985, 42, 242.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. ARS, Beltsville Human Nutrition, Research Center Carbohydrate and Vitamin and Mineral Nutrition Laboratories, USDA, Beltsville, MD, 20705, USA

    Meira Fields

Authors
  1. Meira Fields
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

    John R. J. Sorenson

Rights and permissions

Reprints and permissions

Copyright information

© 1987 The Humana Press Inc.

About this chapter

Cite this chapter

Fields, M. (1987). Dietary Simple Sugars Increase the Severity of Copper Deficiency in Experimental Animals. In: Sorenson, J.R.J. (eds) Biology of Copper Complexes. Experimental Biology and Medicine, vol 16. Humana Press. https://doi.org/10.1007/978-1-4612-4584-1_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-4584-1_10

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-8937-1

  • Online ISBN: 978-1-4612-4584-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation