Skip to main content

The Nutritional Causes of Large Bowel Cancer

Data from the Melbourne Colorectal Cancer Study and A 25 Year World Literature Overview, 1965–1989

  • Chapter

Part of the book series: Experimental Biology and Medicine ((EBAM,volume 23))

Abstract

Colorectal cancer is one of the commonest cancers in developed countries and worldwide, there are over 500,000 new cases each year [1] and over 300,000 deaths are directly attributable to this cancer. An understanding of the causes and the possibilities for prevention of this cancer are therefore of global interest and importance. This communication outlines “The Melbourne Colorectal Cancer Study” and the major findings of the study so far, focuses in detail on the nutritional findings of the study and then compares these to an overview of the literature during the previous 25 years, to conclude with our current understanding of the nutritional causes of large bowel cancer.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Muir CS, Parkin DSM. The world cancer burden: Prevent or perish. Br Med J 290: 5–6, 1985.

    Article  CAS  Google Scholar 

  2. Kune GA, Kune S. The Melbourne colorectal cancer study. A description of the investigation. University of Melbourne, Department of Surgery publication. ISBN 0 86839 569 X, pp 1–31, 1986.

    Google Scholar 

  3. Kune GA, Kune S. New design to examine colorectal cancer cause and survival. Dig Surg 4: 156–159, 1987.

    Article  Google Scholar 

  4. Kune S, Kune GA, Watson LF. The Melbourne colorectal cancer study: Incidence findings by age, sex, site, migrants and religion. Int J Epidemiol 15: 483–493, 1986.

    Article  CAS  Google Scholar 

  5. Kune GA, Kune S, Watson LF. The role of heredity in the etiology of large bowel cancer: Data from the Melbourne colorectal cancer study. World J Surg 13: 124–131, 1989.

    Article  CAS  Google Scholar 

  6. Kune GA, Kune S, Watson LF. History of colorectal polypectomy and risk of subsequent colorectal cancer. Br J Surg 74: 1064–1065, 1987.

    Article  CAS  Google Scholar 

  7. Kune GA, Kune S, Watson LF. Children, age at first birth and colorectal cancer risk. Data from the Melbourne colorectal cancer study. Am J epidemiol 129: 533–542, 1989.

    CAS  Google Scholar 

  8. Kune GA, Kune S, Field B, Watson LF. The role of chronic constipation, diarrhea and laxative use in the etiology of large bowel cancer. Data from the Melbourne colorectal cancer study. Dis Colon Rectum 31: 507–512, 1988.

    Article  CAS  Google Scholar 

  9. Kune GA, Kune S, Watson LF. Oral contraceptive use does not protect against large bowel cancer. Contraception (submitted 1989 ).

    Google Scholar 

  10. Kune GA, Kune S, Watson LF. Colorectal cancer risk, chronic illnesses, operations and medication: Case control results from the Melbourne colorectal cancer study. Cancer Res 48: 4399–4404, 1988.

    CAS  Google Scholar 

  11. Kune GA, Kune S, Watson LF. Large bowel cancer after cholecystectomy. Am J Surg 156: 359–362, 1988.

    Article  CAS  Google Scholar 

  12. Skegg DCG. Potential for bias in case control studies of oral contraceptives and breast cancer. Am J Epidemiol 127: 205–212, 1988.

    CAS  Google Scholar 

  13. Nankin JH, Nomura AMJ, Lee J. Reproducibility of a diet history questionnaire in a case control study of breast cancer. Am J Clin Nutr 37: 981–985, 1983.

    Google Scholar 

  14. Chu S, Kolonel LN, Nankin JH. A comparison of frequency and quantitative dietary methods for epidemiological studies of diet and disease. Am J Epidemiol 119: 323–334, 1984.

    CAS  Google Scholar 

  15. Lee J, Kolonel LN, Nankin JH. Cholesterol intake as measured by unquantified and quantified food frequency interview: Implications for epidemiological research. Int J Epidemiol 14: 249–253, 1985.

    Article  CAS  Google Scholar 

  16. Kune S, Kune GA, Watson LF. Observations on the reliability and validity of the design and diet history method in the Melbourne colorectal cancer study. Nutr Cancer 9: 5–20, 1987.

    Article  CAS  Google Scholar 

  17. Boutron MC, Gaivre J, Milan C, Lorcerie B, Esteve J. A comparison of two diet history questionnaires that measure usual food intake. Nutr Cancer 12: 83–91, 1989.

    Article  CAS  Google Scholar 

  18. Kune S, Kune GA, Watson LF. Case-control study of dietary etiological factors: The Melbourne colorectal cancer study. Nutr Cancer 9: 21–42, 1987.

    Article  CAS  Google Scholar 

  19. Kune S, Kune GA, Watson LF. Case-control study of alcoholic beverages as etiological factors: The Melbourne colorectal cancer study. Nutr Cancer 9: 4356, 1987.

    Google Scholar 

  20. Kune GA, Kune S, Watson LF. Dietary sodium and potassium intake and colorectal cancer risk. Nutr Cancer (in press for December 1989).

    Google Scholar 

  21. Kune GA, Kune S, Watson LF. Body weight and physical activity as predictors of colorectal cancer risk. Nutr Cancer (in press for January 1990).

    Google Scholar 

  22. Higginson J. Etiological factors in gastrointestinal cancer in man. J Nat Cancer Inst 37: 527–545, 1966.

    CAS  Google Scholar 

  23. Wynder EL, Shigematsu T. Environmental factors of cancer of the colon and rectum. Cancer 20: 1520–1561, 1967.

    Article  CAS  Google Scholar 

  24. Wynder EL, Kajitani T, Ishikawa S, Dodo H, Takano A. Environmental factors of cancer of the colon and rectum. II. Japanese epidemiological data. Cancer 23: 1210–1220, 1969.

    Article  CAS  Google Scholar 

  25. Bjelke E. Case-control study of cancer of the stomach, colon, and rectum. Proc 10th Int Cancer Congress, Vol 5. Chicago:Year Book, pp 320–334, 1971.

    Google Scholar 

  26. Haenszel W, Berg JW, Segi M, Kurihara M, Locke FB. Large-bowel cancer in Hawaiian Japanese. J Natl Cancer Inst 51: 1765–1779, 1973.

    CAS  Google Scholar 

  27. Modan B, Barell V, Lubin F, Modan M. Dietary factors and cancer in Israel. Cancer Res 35: 3503–3506, 1975.

    CAS  Google Scholar 

  28. Modan B, Barell V, Lubin F, Modan M, Greenberg RA, Graham S. Low-fiber intake as an etiologic factor in cancer of the colon. J Natl Cancer Inst 55: 15–18, 1975.

    CAS  Google Scholar 

  29. Dales LG, Friedman GD, Ury HK, Grossman S, Williams SR. A case-control study of relationships of diet and other traits to colorectal cancer in American blacks. Am J Epidemiol 109: 132–144, 1978.

    Google Scholar 

  30. Graham S, Dayal H, Swanson M, Mittelman A, Wilkinson G. Diet in the epidemiology of cancer of the colon and rectum. J Natl Cancer Inst 61: 709–714, 1978.

    CAS  Google Scholar 

  31. Jain M, Cook GM, Davis FG, Grace MG, Howe GR, Miller AB. A case-control study of diet and colo- rectal cancer. Int J Cancer 26: 757–768, 1980.

    Article  CAS  Google Scholar 

  32. Haenszel W, Locke FB, Segi M. A case-control study of large bowel cancer in Japan. JNCI 64: 17–22, 1980.

    CAS  Google Scholar 

  33. Vobecky J, Caro J, Devroede G. A case-control study of risk factors for large bowel carcinoma. Cancer 51: 1958–1963, 1983.

    Article  CAS  Google Scholar 

  34. Howe GR, Miller AB, Jain M, Cook G. Dietary factors in relation to the etiology of colorectal cancer. Cancer Detection & Prevention 5: 331–334, 1982.

    CAS  Google Scholar 

  35. Tuyns AJ, Pequignot G, Gignoux M, Valla A. Cancers of the digestive tract, alcohol and tobacco. Int J Cancer 30: 9–11, 1982.

    Article  CAS  Google Scholar 

  36. Potter JD, McMichael AJ, Bonett AZ. Diet, alcohol and large-bowel cancer: A case control study. Proc Nutr Soc Aust 7: 123–126, 1982.

    Google Scholar 

  37. Maclennan R, Correa P, Heilbrun L, Newell G, Pollack E. Report of a workshop: Cancers of the colon and rectum. Nat Cancer Inst Monograph 62: 145–149, 1982.

    CAS  Google Scholar 

  38. Ward K, Moriarty KJ, O’Neill S, Clark ML, Dean G. Alcohol and colo-rectal cancer. Gut 24: A981, 1983.

    Article  Google Scholar 

  39. Manousos O, Day NE, Trichopoulos D, Gerovassilis F, Tzonou A, Polychronopoulou A. Diet and colorectal cancer: A case-control study in Greece. Int J Cancer 32: 1–5, 1983.

    Article  CAS  Google Scholar 

  40. Miller AB, Howe GR, Jain M, Craib KJP, Harrison L. Food items and food groups as risk factors in a case-control study of diet and colo-rectal cancer. Int J Cancer 32: 155–161, 1983.

    Article  CAS  Google Scholar 

  41. Macquart-Moulin G, Durbec J-P, Cornee J, Berthezene P, Southgate DAT. Diet and colorectal cancer. Gastroenterol Clin Biol 7: 277–286, 1983.

    CAS  Google Scholar 

  42. Pickle LW, Greene MH, Ziegler RG, Toledo A, Hoover R, Lynch T, Fraumeni JF Jr. Colorectal cancer in rural Nebraska. Cancer Res 44: 363–369, 1984.

    CAS  Google Scholar 

  43. McMichael AJ, Potter JD. Diet and colon cancer: Integration of the descriptive, analytic, and metabolic epidemiology. Natl Cancer Inst Monogr 69: 223–228, 1985.

    CAS  Google Scholar 

  44. Heilbrun LK, Nomura A, Hankin JH, Stemmermann GN. Dietary vitamin D and calcium and risk of colorectal cancer. Lancet 20: 925, 1985.

    Article  Google Scholar 

  45. Tajima K, Tominaga S. Dietary habits and gastro-intestinal cancers: A comparative case-control study of stomach and large intestinal cancers in Nagoya, Japan. Jpn J Cancer Res (Gann) 76: 705–716, 1985.

    CAS  Google Scholar 

  46. Bristol JB, Emmett PM, Heaton KW, Williamson RCN. Sugar, fat, and the risk of colorectal cancer. Br Med J 291: 1467–1470, 1985.

    Article  CAS  Google Scholar 

  47. Berta J-L, Coste T, Rautureau J, Guilloud-Bataille M, Pequignot G. Alimentation et cancers recto-coliques. Resultats d’une etude (cas-temoin). Gastroenterol Clin Biol 9: 348–353, 1985.

    CAS  Google Scholar 

  48. Potter JD, McMichael AJ. Diet and cancer of the colon and rectum: A case-control study. JNCI 76: 557–569, 1986.

    CAS  Google Scholar 

  49. Macquart-Moulin G, Riboli E, Cornee J, Charnay B, Berthezene P, Day N. Case-control study on colorectal cancer and diet in Marseilles. Int J Cancer 38: 183–191, 1986.

    Google Scholar 

  50. Lyon JL, Mahoney AW, West DW, Gardner JW, Smith KR, Sorenson AW, Stanish W. Energy intake: Its relationship to colon cancer risk. JNCI 78: 853–861, 1987.

    CAS  Google Scholar 

  51. Tuyns AJ, Haelterman M, Kaaks R. Colorectal cancer and the intake of nutrients: Oligosaccharides are a risk factor, fats are not. A case-control study in Belgium. Nutr Cancer 10: 181–196, 1987.

    Article  CAS  Google Scholar 

  52. Tuyns A. Salt and gastrointestinal cancer. Nutr Cancer 11: 229–232, 1988.

    Article  CAS  Google Scholar 

  53. Tuyns AJ, Kaaks R, Haelterman M. Colorectal cancer and the consumption of foods: A case-control study in Belgium. Nutr Cancer 11: 189–204, 1988.

    Article  CAS  Google Scholar 

  54. Graham S, Marshall J, Haughey B, Mittelman A, Swanson M, Zielezny M, Byers T, Wilkinson G, West D. Dietary epidemiology of cancer of the colon in Western New York. Am J Epidemiol 128: 490–503, 1988.

    CAS  Google Scholar 

  55. Phillips RL. Role of life-style and dietary habits in risk of cancer among Seventh-Day Adventists. Cancer Res 35: 3513–3522, 1975.

    CAS  Google Scholar 

  56. Vlajinac H, Adanja B, Jarebinski M. Case-control study of the relationship of diet and colon cancer. Arch Geschwulstforsch 57: 493–499, 1987.

    CAS  Google Scholar 

  57. Kabat GC, Howson CP, Wynder EL. Beer consumption and rectal cancer. Int J Epidemiol 15: 494–501, 1986.

    Article  CAS  Google Scholar 

  58. Slattery ML, Sorenson AW, Ford MH. Dietary calcium intake as a mitigating factor in colon cancer. Am J Epidemiol 128: 504–514, 1988.

    CAS  Google Scholar 

  59. Lyon JL, Mahoney AW. Fried foods and the risk of colon cancer. Am J Epidemiol 128: 1000–1006, 1988.

    CAS  Google Scholar 

  60. Slattery ML, Sorenson AW, Mahoney AW, French TK, Kritchevsky D, Street JC. Diet and colon cancer: Assessment of risk by fiber type and food source. J Natl Cancer Inst 80: 1474–1480, 1988.

    Article  CAS  Google Scholar 

  61. Martinez I, Torres R, Frias Z, Colon JR, Fernandez N. Factors associated with adenocarcinomas of the large bowel in Puerto Rico. Adv Med Onc Res Educ 3: 45–52, 1975.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1990 The Humana Press Inc.

About this chapter

Cite this chapter

Kune, G., Kune, S., Field, B., Watson, L. (1990). The Nutritional Causes of Large Bowel Cancer. In: Prasad, K.N., Meyskens, F.L. (eds) Nutrients and Cancer Prevention. Experimental Biology and Medicine, vol 23. Humana Press. https://doi.org/10.1007/978-1-4612-4516-2_16

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-4516-2_16

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-8856-5

  • Online ISBN: 978-1-4612-4516-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics