Abstract
In the mid-1960’s the interesting phenomenon of initiation and promotion had been established, but very little was known about the chemopreventive approach to carcinogenesis. Many investigators thought that a free radical mechanism was involved. Free radicals would cause tissue damage and peroxidation. Tissue damage also seemed to be related to the cancer process. The greater the tissue damage, the higher the number of cancers in many experiments.
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Shamberger, R.J. (1990). Selenium and Vitamin E in Cancer Prevention. In: Prasad, K.N., Meyskens, F.L. (eds) Nutrients and Cancer Prevention. Experimental Biology and Medicine, vol 23. Humana Press. https://doi.org/10.1007/978-1-4612-4516-2_14
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DOI: https://doi.org/10.1007/978-1-4612-4516-2_14
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