Effects of Ethanol on Contractility and Membrane Currents of Cardiac Tissue

  • M. J. Su
  • S. O. Lin
Part of the Experimental Biology and Medicine book series (EBAM, volume 21)


The molecular mechanisms underlying the pharmacological actions of ethanol are presently unknown. There is, however, an abundance of experimental evidence which indicates that general anesthetic agents alter the physical properties of biological membranes (6). Ethanol has been known to perturb the lipid portion of synaptic membrane (2,9,10). It is likely that these changes may alter the properties of ionic channels on the membrane.


Left Atrium Action Potential Duration Membrane Current Tyrode Solution Ventricular Cell 
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Copyright information

© The Humana Press Inc. 1989

Authors and Affiliations

  • M. J. Su
    • 1
  • S. O. Lin
    • 1
  1. 1.Pharmacological Institute, College of MedicineNational Taiwan UniversityTaipeiTaiwan, R.O.C.

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