Effects of Ethanol on Contractility and Membrane Currents of Cardiac Tissue
The molecular mechanisms underlying the pharmacological actions of ethanol are presently unknown. There is, however, an abundance of experimental evidence which indicates that general anesthetic agents alter the physical properties of biological membranes (6). Ethanol has been known to perturb the lipid portion of synaptic membrane (2,9,10). It is likely that these changes may alter the properties of ionic channels on the membrane.
KeywordsLeft Atrium Action Potential Duration Membrane Current Tyrode Solution Ventricular Cell
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