The EBV DR Enhancer Contains two Functionally Different Domains: A and B.

  • Anna Chevallier Greco
  • H. Gruffat
  • E. Manet
  • Alain Sergeant
Chapter
Part of the Experimental Biology and Medicine book series (EBAM, volume 20)

Abstract

The Epstein-Barr Virus (EBV) DR promoter controls the expression of early mRNAs consisting of 102 bp repeats from the IR4 region (Figure 1A and 1E) (1). The duplicated left (DL) promoter is almost a perfect copy of the DR promoter region (Figure 1F) (1) and directs the expression of early mRNAs containing short tandem repeats, the IR2 repeats which are partially homologous to the IR4 repeats (4, 5, 6).

Keywords

Chloramphenicol 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    G. Laux, U. K. Freese et al., J. Virol. 56, 987 (1985).PubMedGoogle Scholar
  2. 2.
    A. Chevallier-Greco, E. Manet et al. EMBO J. 5, 3243 (1986).PubMedGoogle Scholar
  3. 3.
    A. Chevallier Greco, E. Manet et al., in EBV and Human Dis., P. H. Levine, D. V. Ablashi et al., Eds. (Humana press, Clifton, New Jersey, 1987), p.157.Google Scholar
  4. 4.
    T. Dambaugh and E. Kieff, J. Virol. 44, 823 (1982).PubMedGoogle Scholar
  5. 5.
    U. K. Freese, G. Laux et al, J. Virol. 48,731 (1983).PubMedGoogle Scholar
  6. 6.
    K. T. Jeang and S. G. Hayward, J. Virol. 48,135 (1983).PubMedGoogle Scholar
  7. 7.
    P. Chavrier, H. Gruffat et al., J. Virol, in press (1989).Google Scholar
  8. 8.
    J. K. Countryman, H. Jenson et al., Cancer Cells 4, 517 (1986).Google Scholar
  9. 9.
    N. Takada, N. Shimizu et al., J. Virol. 57, 1016 (1986).PubMedGoogle Scholar
  10. 10.
    A. Chevallier Greco, H. Gruffat et al., J. Virol. in press (1989)Google Scholar
  11. 11.
    J. M. Hardwick, P. M. Lieberman et al., J. Virol. 62, 2274 (1988).PubMedGoogle Scholar

Copyright information

© The Humana Press Inc. 1989

Authors and Affiliations

  • Anna Chevallier Greco
    • 1
  • H. Gruffat
    • 1
  • E. Manet
    • 1
  • Alain Sergeant
    • 1
  1. 1.Laboratoire de Virologie MoléculaireEcole Normale Supérieure de LyonLyon Cedex 07France

Personalised recommendations