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Nonimmunologic Mechanisms of Glomerular Injury

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Pathology Reviews · 1989

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Abstract

The importance of immunologic processes in the pathogenesis of glomerulonephritis has long been recognized, and over the past 30 years considerable progress has been made. However, the importance of nonimmunologic factors in causing glomerular damage has only recently been emphasized in spite of many older studies on the effects of reduction of functioning renal mass, manipulation of diet, and induction of high blood pressure. Furthermore, the possibility that these factors might be important in the pathogenesis of chronic renal disease in general has received little attention.

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Authors and Affiliations

  1. Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    Jean L. Olson M.D. & Robert H. Heptinstall

  2. Department of Pathology, The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD, 21205, USA

    Robert H. Heptinstall

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  1. Jean L. Olson M.D.
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Editors and Affiliations

  1. Department of Pathology and Cell Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

    Emanuel Rubin MD (Gonzalo Aponte Professor and Chairman) & Ivan Damjanov MD (Professor) (Gonzalo Aponte Professor and Chairman) &  (Professor)

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Olson, J.L., Heptinstall, R.H. (1989). Nonimmunologic Mechanisms of Glomerular Injury. In: Rubin, E., Damjanov, I. (eds) Pathology Reviews · 1989. Humana Press. https://doi.org/10.1007/978-1-4612-4502-5_9

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