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The Search for Bioactive Compounds from Microorganisms pp 281–302Cite as

Selection of Microbial Sources of Bioactive Compounds

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Part of the book series: Brock/Springer Series in Contemporary Bioscience ((BROCK/SPRINGER))

Abstract

Soon after penicillin was rediscovered as an antibiotic and named the “yellow magic medicine,” a new field of applied microbiology, i.e., that is, antibiotic screening, was introduced, especially by S.A. Waksman, who discovered streptomycin. A large number of bioactive metabolites have been isolated from various microbial sources, such as actinomycetes, bacteria, fungi, mushrooms, etc., but actinomycetes have proved to be the most important as antibiotic producers. The new antibiotics found in 1980 were derived from actinomycetes (80.4%), bacteria (11.4%), and fungi-mushrooms (8.3%); about 75% of those discovered during 1971–1980 were also from this group of microorganisms (Higashide and Yamamoto, 1982). An efficient way of finding new bioactive metabolites is by the discovery of new microorganisms, and many approaches have been used.

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Authors
  1. Yuzuru Iwai
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  2. Yōko Takahashi
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Editor information

Editors and Affiliations

  1. Research Center for Biological Function, The Kitasato Institute, and School of Pharmaceutical Sciences, Kitasato University, Minato-ku, Tokyo, 108, Japan

    Satoshi Ōmura Ph.D.

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© 1992 Spring-Verlag New York, Inc.

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Iwai, Y., Takahashi, Y. (1992). Selection of Microbial Sources of Bioactive Compounds. In: Ōmura, S. (eds) The Search for Bioactive Compounds from Microorganisms. Brock/Springer Series in Contemporary Bioscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4412-7_15

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  • DOI: https://doi.org/10.1007/978-1-4612-4412-7_15

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8761-2

  • Online ISBN: 978-1-4612-4412-7

  • eBook Packages: Springer Book Archive

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