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Office Gynecology pp 111–120Cite as

Ectopic Pregnancy

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Abstract

An ectopic pregnancy (EP) occurs whenever implantation of the fertilized ovum takes place on any tissue other than endometrium, including abnormal intrauterine implantations (the uterine cornua, uterine cervix) as well as more obvious extrauterine implantations (fallopian tube, peritoneal cavity). The first historical reference made to this entity was by the Arabic writer Albucasis in the year a.d.. 963.1 Described in 1693 by Busiere upon the examination of the body of an executed prisoner,2 it was finally discussed in print in the 17th century in F. Mariceau’s obstetrical textbook.3 Originally, EP was treated by observation, starvation, purgation, ergot, and electrocution and had a maternal mortality of nearly 70%. The first successful operation was performed March 1, 1883, when Lawson Tait performed a salpingectomy for the treatment of an ectopic pregnancy.4

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References

  1. Albucasis. Altrasrif (11th century). English translation: Oxford, 1778.

    Google Scholar 

  2. Ectopic pregnancy. In: Mattingly RF, Thompson JD, eds. TeLinde’s Operative Gynecology. Philadelphia, Pa: JB Lippincott Company; 1985: 429–448.

    Google Scholar 

  3. Manceau, F. Traité des Femmes Grosses. Paris, 1694.

    Google Scholar 

  4. Tait, RL. Ectopic Pregnancy and Pelvic Hematocoel (lecture). Birmingham, England: Journal Printing Works, 1888.

    Google Scholar 

  5. Ectopic pregnancy surveillance, United States, 1970–1987. MMWR. 1988; 39 (SS-4): 9–17.

    Google Scholar 

  6. Ectopic pregnancy surveillance, United States, 1984 and 1985. MMWR 1988; 7: 637.

    Google Scholar 

  7. DeCherney A, Kase N. The conservative surgical management of unruptured ectopic pregnancy. Obstet Gynecol. 1979; 54: 451.

    PubMed  CAS  Google Scholar 

  8. Barnes AB, Wennberg CN, Barnes BA. Ectopic pregnancy: incidence and review of determinant factors. Obstet Gynecol Surv. 1983; 38: 345356.

    Google Scholar 

  9. Novy M. Surgical alternatives for ectopics: is conservative treatment best? Contemp Obstet Gynecol. 1983; 21: 91.

    Google Scholar 

  10. Pouly JL, Mahnes H, Mage G, et al. Conservative laparoscopic treatment of 321 ectopic pregnancies. Fertil Steril. 1986; 46: 1093–1097.

    PubMed  CAS  Google Scholar 

  11. Langer R, Bukovsky I, Herman A, et al. Conservative surgery for tubal pregnancy. Fertil Steril. 1982; 38: 427–430.

    PubMed  CAS  Google Scholar 

  12. Altchek A. Ectopic pregnancy in young patients. Contemp Obstet Gynecol. 1984; 22: 133. 29.

    Google Scholar 

  13. Persoud V. Etiology of tubal pregnancy. Obstet Gynecol. 1970; 36: 257.

    Google Scholar 

  14. Ory S. New options for diagnosis and treatment of ectopic pregnancy. JAMA. 1992; 30. 267: 534–537.

    Article  Google Scholar 

  15. Stock RJ. Histopathologic changes in tubal pregnancy. J Reprod Med. 1985; 30: 923–928. 31.

    Google Scholar 

  16. DeCherney, AH. Structure and function of the fallopian tubes following exposure to DES during gestation. Fertil Steril. 1981; 36: 741.

    PubMed  CAS  Google Scholar 

  17. Budowick M, Johnson TRB, Genadry R, et al. 32. The histopathology of the developing tubal ectopic pregnancy. Fertil Steril. 1980; 34: 169.

    PubMed  CAS  Google Scholar 

  18. Berlind M. The contralateral corpus luteuman important factor in ectopic pregnancies. Ob- 33. stet Gynecol. 1960; 16: 51.

    CAS  Google Scholar 

  19. Insunza A, DePablo F, Croxatto HD, et al. On the rate of tubal pregnancy contralateral to the 34. corpus luteum. Acta Obstet Gynecol Scand. 1988; 67: 433–436.

    Article  PubMed  CAS  Google Scholar 

  20. Stratford BF. Abnormalities in early human development. Am J Obstet Gynecol. 1970; 35. 107: 1223.

    Google Scholar 

  21. Pland BJ, Dill FJ, Stylblo C. Embryonic development in ectopic human pregnancy. Teratology. 1976; 14: 315. 36.

    Google Scholar 

  22. Stock, RJ. Histopathology of fallopian tubes with recurrent tubal pregnancy. Obstet Gynecol. 1990; 75: 9–14. 37.

    Google Scholar 

  23. Breen JL. A 21-year survey of 654 ectopic pregnancies. Am J Obstet Gynecol. 1970; 106: 1004.

    PubMed  CAS  Google Scholar 

  24. Spiegelberg O. Zur casuistik den ovarial- 38. schwangenschaft. Arch Gynaekol. 1878; 13: 73.

    Article  Google Scholar 

  25. Wekstein LN. Current perspectives on ectopic pregnancy. Obstet Gynecol Surv. 1985; 40: 259272. 39.

    Google Scholar 

  26. Kadar N, Devore G, Romero R. Discriminatory hCG zone: its use in the sonographic evaluation for ectopic pregnancy. Obstet Gynecol. 1981; 58: 156–161. 40.

    Google Scholar 

  27. Holman JF, Tyrey EL, Hammond CB. A contemporary approach to suspected ectopic pregnancy with use of quantitative and qualitative assays for B-subunit of human chorionic gonadotropin and sonography. Am J Obstet Gynecol. 1984; 150: 151–157.

    PubMed  CAS  Google Scholar 

  28. Pittaway DE, Wentz AC. Evaluation of early pregnancy by serial chorionic gonadotropin determinations: a comparison of methods by receiver operating characteristic curve analysis. Fertil Steril. 1985; 43: 529–533.

    PubMed  CAS  Google Scholar 

  29. Shepherd RW, Patton PE, Novy MJ, et al. Serial B-hCG measurements in the early detection of ectopic pregnancy. Obstet Gynecol. 1990; 75: 417–420.

    PubMed  CAS  Google Scholar 

  30. Fossum GT, Davajan V, Kletzky OA. Early detection of pregnancy with transvaginal ultrasound. Fertil Steril. 1988; 49: 788–791.

    PubMed  CAS  Google Scholar 

  31. Romero R, Kadar N, Castro D, et al. The value of adnexal sonographic findings in the diagnosis of ectopic pregnancy. Am J Obstet Gynecol. 1988; 158: 52–55.

    PubMed  CAS  Google Scholar 

  32. Bateman BG, Nunley WC, Kolp LA, et al. Vaginal sonography findings and hCG dynamics of early intrauterine and tubal pregnancy. Ob-stet Gynecol. 1990; 75: 421–427.

    CAS  Google Scholar 

  33. DeVoe R, Pratt J. Simultaneous intrauterine and extrauterine pregnancy. Am J Obstet Gynecol. 1948; 56: 1119.

    PubMed  CAS  Google Scholar 

  34. Molloy D, Deambrosis W, Keeping D, et al. Multiple-sited (heterotopic) pregnancy after in vitro fertilization and gamete intrafallopian transfer. Fertil Steril. 1990; 53: 1068–1071.

    PubMed  CAS  Google Scholar 

  35. Dimitry ES, Subak-Sharpe R, Mills M, et al. Nine cases of heterotopic pregnancies in four years of in vitro fertilization. Fertil Steril. 1990; 53: 107–110.

    PubMed  CAS  Google Scholar 

  36. Bello GV, Schonholz D, Mashirpur J, et al. Combined pregnancy: the Mount Sinai experience. Obstet Gynecol Surv. 1986; 41: 603–613.

    Article  PubMed  CAS  Google Scholar 

  37. Mildwidsky A, Adoni A, Dalti Z. Chorionic gonadotropin and progesterone levels in ectopic pregnancy. Obstet Gynecol. 1977; 50: 145–147.

    Google Scholar 

  38. Radwanska E, Frankenberg J, Allen EI. Plasma progesterone levels in normal and abnormal early human pregnancy. Fertil Steril. 1978; 30: 398–402.

    PubMed  CAS  Google Scholar 

  39. Matthews CP, Coulson PB, Wild RA. Serum progesterone levels as an aid in the diagnosis of ectopic pregnancy. Obstet Gynecol. 1986; 68: 390–394.

    PubMed  CAS  Google Scholar 

  40. Yeko TR, Gorrill MJ, Hughes LH, et al. Timely diagnosis of early ectopic pregnancy using a single blood progesterone measurement. Fertil Steril. 1987; 48: 1048–1050.

    PubMed  CAS  Google Scholar 

  41. Stovall TG, Ling FW, Cope BJ, et al. Prevent-ing ruptured ectopic pregnancy with a single 43. serum progesterone. Am J Obstet Gynecol. 1989; 160: 1425–1431.

    PubMed  CAS  Google Scholar 

  42. Pouly JL, Mahnes H, Mage G, et al. Conser- 44. vative laparoscopic treatment of 321 ectopic pregnancies. Fertil Steril. 1986; 46: 1093–1097.

    PubMed  CAS  Google Scholar 

  43. Leach RE, Ory SJ. Modern management of ectopic pregnancy. J Reprod Med. 1989; 34: 324–338.

    PubMed  CAS  Google Scholar 

  44. Stovall TG, Ling FW, Buster JE. Outpatient chemotherapy of unruptured ectopic pregnan-cy. Fertil Steril. 1989; 51: 435–438.

    PubMed  CAS  Google Scholar 

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Authors
  1. James V. Brasch
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Editors and Affiliations

  1. Stritch School of Medicine, Loyola University of Chicago, Maywood, IL, 60153, USA

    John V. Knaus D.O. (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief) & John H. Isaacs M.D. (Professor of Obstetrics and Gynecology, Gynecologist-in-Chief) (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief) &  (Professor of Obstetrics and Gynecology, Gynecologist-in-Chief)

  2. Department of Obstetrics and Gynecologic, St. Francis Hospital, Evanston, IL, 60202, USA

    John V. Knaus D.O. (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief) (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief)

  3. Section of Gynecologic Oncology, St. Francis Hospital, Evanston, IL, 60202, USA

    John V. Knaus D.O. (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief) (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief)

  4. St. Francis Hospital, Evanston, IL, 60202, USA

    John H. Isaacs M.D. (Professor of Obstetrics and Gynecology, Gynecologist-in-Chief) (Professor of Obstetrics and Gynecology, Gynecologist-in-Chief)

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© 1993 Springer-Verlag New York, Inc.

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Brasch, J.V. (1993). Ectopic Pregnancy. In: Knaus, J.V., Isaacs, J.H. (eds) Office Gynecology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4340-3_9

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  • DOI: https://doi.org/10.1007/978-1-4612-4340-3_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8740-7

  • Online ISBN: 978-1-4612-4340-3

  • eBook Packages: Springer Book Archive

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