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Human Immunodeficiency Virus (HIV) and Hepatitis

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Office Gynecology

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Abstract

Viral hepatitis is caused by five known enterically or parenterally transmitted viruses. The disease can be severe, especially in pregnancy, and chronic liver disease results from infection with two of the five agents. In addition, congenital infection may occur. Likewise, human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) are becoming increasingly common and are also transmitted vertically. Unique manifestations of HIV infection in women are only recently receiving emphasis in the medical literature. In this chapter the epidemiology, clinical manifestations, treatment, and prevention of these important viral diseases in women and their offspring are reviewed.

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References

  1. Centers for Disease Control. Delta hepatitis. MMWR. 1984;33:493.

    Google Scholar 

  2. Choo Q-L, Kuo G, Weiner AJ, et al. Isolation of a cDNA clone derived from a blood-borne non-A, non-B hepatitis genome. Science. 1989;224:359–362.

    Article  Google Scholar 

  3. Ramalingaswami V, Purcell RH. Waterborne non-A, non-B hepatitis. Lancet. 1988;1:571–3.

    Article  PubMed  CAS  Google Scholar 

  4. Centers for Disease Control. Hepatitis A among drug users. MMWR. 1988;37:297–300,305.

    Google Scholar 

  5. Nobel RL, Kane MA, Reeves SA, et al. Post transfusion hepatitis A in a neonatal intensive care unit. JAMA. 1984;252:2711-S.

    Article  Google Scholar 

  6. Centers for Disease Control. Protection against viral hepatitis. MMWR. 1990;39:1–26.

    Google Scholar 

  7. James S, Disaia P, Hammond CP, et al. General medical and surgical diseases in pregnancy. Danforth Obstetrics and Gynecology. 1990;508–509,540–541.

    Google Scholar 

  8. Snydman D. Hepatitis in pregnancy. N Engl J Med. 1985;313:1398–1401.

    Article  PubMed  CAS  Google Scholar 

  9. Oren I, Hershow R, Ben-Porath E, et al. A common source outbreak of fulminant hepatitis B in a hospital. Ann Intern Med. 1989;110:691–698.

    PubMed  CAS  Google Scholar 

  10. Sherlock S. Predicting progression of acute type B hepatitis to chronicity. Lancet. 1976; 2:354–356.

    Article  PubMed  CAS  Google Scholar 

  11. Centers for Disease Control. Hepatitis B virus: a comprehensive strategy for eliminating transmission in the United States through universal childhood vaccination. MMWR. 1991;40 (RR13):1–19.

    Google Scholar 

  12. Koretz R. Universal prenatal hepatitis B screening. Obstet Gynecol 1989;74;808–814.

    CAS  Google Scholar 

  13. Reeink HW, Cafever, Scishut, et al. Prevention of chronic HBsAg carrier state in infants of HBsAg positive mothers, by hepatitis B immunoglobulin. Lancet. 1979;1:436–438.

    Article  Google Scholar 

  14. Kane M, Hadler S, Margolis H. Routine prenatal screening for hepatitis B surface antigen. JAMA. 1988;259:408–409.

    Article  PubMed  CAS  Google Scholar 

  15. Rocca G, Poli G, Gerard P, et al. Family clustering of delta infection. Viral hepatitis and delta infection. New York: Alan R. Liss; 1984:133–137.

    Google Scholar 

  16. Rizzetto M, Verma G, Recchia 5, et al. Chronic HBsAg hepatitis with intrahepatic expression of delta antigen. Ann Intern Med. 1983;98:437–441.

    PubMed  CAS  Google Scholar 

  17. Dienstag JL. Non-A non-B hepatitis: recognition, epidemiology, and clinical features. Gastroenterology. N Engl J Med. 1983;84:133–137.

    Google Scholar 

  18. Davis G, Baiart LA, Schiff ER, et al. Treatment of chronic hepatitis C with recombinant interferon alpha. N Engl J Med. 1989;321: 1501–1506.

    Article  PubMed  CAS  Google Scholar 

  19. Davis GL, Baiart LA, Schiff ER, et al. Treatment of chronic hepatitis C with recombinant interferon alpha: a multicenter randomized, controlled trial. N Engl J Med. 1989; 321(22): 1501–1506.

    Article  PubMed  CAS  Google Scholar 

  20. Gust I, Purcell R. Report of a workshop: waterborne non-A, non B hepatitis. J Infect Dis. 1987;156:630–635.

    Article  PubMed  CAS  Google Scholar 

  21. Ellerbrock T, Rogers M. Epidemiology of human immunodeficiency virus infection in women in the United States. Obstet Gynecol Clin North Am. 1990;17:523–541.

    PubMed  CAS  Google Scholar 

  22. Centers for Disease Control. The second 100,000 cases of acquired immunodeficiency syndrome—United States, June 1981—December 1991. MMWR. 1992;41:28–29.

    Google Scholar 

  23. Centers for Disease Control. Update: acquired Immunodeficiency syndrome—United States, 1981–1990. MMWR. 1991;40:358–363,369.

    Google Scholar 

  24. Centers for Disease Control. AIDS in women—United States. MMWR. 1990;39:845–846.

    Google Scholar 

  25. Marmor M, Weiss LR, Leyden M, et al. Possible female-to-female transmission of human immunodeficiency virus (letter). Ann Intern Med. 1986; 105:969.

    PubMed  CAS  Google Scholar 

  26. Monzon OT, Capelian JMB. Female-to-female transmission of HIV (letter). Lancet. 1987; 2:40–41.

    Article  PubMed  CAS  Google Scholar 

  27. Chu S, Buehler J, Fleming P, et al. Epidemiology of reported cases of AIDS in lesbians, United States; 1980–1989. Am J Public Health. 1990;80:1380–1381.

    Article  PubMed  CAS  Google Scholar 

  28. Minkoff H, DeHovitz J. Care of women infected with the human immunodeficiency virus. JAMA. 1991;266:2253–2258.

    Article  PubMed  CAS  Google Scholar 

  29. Allen M. Primary care of women infected with the human immunodeficiency virus. Obstet Gynecol Clin North Am. 1990;17:557–567.

    PubMed  CAS  Google Scholar 

  30. Kess S, Bresolin L, Henning J. HIV early care. AMA Physician Guidelines. 1990;1–15.

    Google Scholar 

  31. Centers for Disease Control. Recommendations for prophylaxis against Pneumocystis carinii pneumonia for adults and adolescents infected with human immunodeficiency virus. MMWR. 1992;41:1–11.

    Google Scholar 

  32. Iman N, Carpenter C, Mayer K, et al. Hierarchical pattern of mucosal Candida infections in HIV-seropositive women. Am J Med. 1990;89:142–146.

    Article  Google Scholar 

  33. Rhoads J, Wright C, Redfield R, et al. Chronic vaginal candidiasis in women with human immunodeficiency virus infection. JAMA. 1987;257(2):3105–3107.

    Article  PubMed  CAS  Google Scholar 

  34. Hoegsberg B, Abulafia 0, Sedlis A, et al. Sexually transmitted diseases and HIV infection among women with pelvic inflammatory disease. Amer J Obstet Gynecol. 1990;163:1135–1139.

    CAS  Google Scholar 

  35. Safrin S, Dattel B, Hauer L, et al. Seroprevalence and epidemiologic correlates of human immunodeficiency virus in women with acute pelvic inflammatory disease. Obstet Gynecol. 1990;75:666–670.

    PubMed  CAS  Google Scholar 

  36. Centers for Disease Control. Sexually transmitted diseases: therapy guidelines. MMWR. 1989;38:5–15.

    Google Scholar 

  37. Peterson HB, Galaid EI. Pelvic inflammatory disease: review of therapeutic options. Rev Infect Dis. 1990;12:S656–664.

    Article  PubMed  Google Scholar 

  38. Holmes K, Kreiss J. Heterosexual transmission of human immunodeficiency virus: overview of a neglected aspect of the AIDS epidemic. J Acq Immun Def Synd. 1988;1(6):602–610.

    CAS  Google Scholar 

  39. Abstracts of The Third International Conference in AIDS. Washington, DC; 1987:25.

    Google Scholar 

  40. Pomerantz R, DeLaMonte S, Donegan P, et al. Human immunodeficiency virus infection of the uterine cervix. Ann Intern Med. 1988; 108(3):321–327.

    PubMed  CAS  Google Scholar 

  41. Tramont EC. Syphilis in the AIDS era. N Engl Med. 1987;316:1600–1601.

    Article  CAS  Google Scholar 

  42. Musher DM, Hamill RJ, Baughn RE. Effect of human immunodeficiency virus in the course of syphilis and on the response to treatment. Ann Intern Med. 1990;113:872–881.

    PubMed  CAS  Google Scholar 

  43. Saxon A. Immediate hypersensitivity reactions to beta lactam antibiotics. Ann Intern Med. 1987;107:204–215.

    PubMed  CAS  Google Scholar 

  44. Allen M. Primary care of women infected with the human immunodeficiency virus. Obstet Gynecol Clinic North Am. 1990;17(3):557–567.

    CAS  Google Scholar 

  45. Erlich KS, Jacobson MA, Kochler JE, et al. Foscarnet therapy for severe acyclovir-resistant herpes simplex virus type-Z infections in patients with the acquired immunodeficiency syndrome. Ann Intern Med. 1989;110:710–713.

    PubMed  CAS  Google Scholar 

  46. Klug S, Lewandowski C, Merker H, et al. In-vitro and invivo studies on the prenatal toxicity of five virustatic nucleoside analogues in comparison to acyclovir. Arch Toxicol. 1991; 65:283–291.

    Article  PubMed  CAS  Google Scholar 

  47. Sillman F, Stanek A, Sedlis A. The relationship between human papilloma virus and lower genital neoplasia in immunosuppressed women. Am J Obstet Gynecol. 1984;150:300–308.

    PubMed  CAS  Google Scholar 

  48. Maiman M, Fruchter R, Serure, et al. Human immunodeficiency virus infection and cervical neoplasia. Gynecol Oncol. 1990;38:377–382.

    Article  PubMed  CAS  Google Scholar 

  49. Carpenter C, Mayer K, Stein M, et al. Human immunodeficiency virus infection in North American women: experience with 200 cases and a review of the literature. Medicine. 1991;70(5):307–325.

    Article  PubMed  CAS  Google Scholar 

  50. Center for Disease Control. Risk for cervical disease in HIV-infected women—New York City. MMWR. 1990;39:846–849.

    Google Scholar 

  51. Maiman M, Tarricone N, Vieira J, et al. Colposcopy evaluation of human immunodeficiency virus-seropositive women. Obstet Gynecol. 1991;78(l):84–88.

    PubMed  CAS  Google Scholar 

  52. Senanayake P, Kramer DG. Contraception and the etiology of pelvic inflammatory disease: new perspectives. Am J Obstet Gynecol. 1980;138:852–860.

    PubMed  CAS  Google Scholar 

  53. Minkoff H, Nanda D, Menez R. Pregnancies resulting in infants with acquired immunodeficiency syndrome or AIDS-related complex: follow-up of mothers, children, and subsequently born children. Obstet Gynecol. 1987; 69:285–291.

    PubMed  CAS  Google Scholar 

  54. Selwyn P, Schoenbaum E, Davenny K. Prospective study of human immunodeficiency virus infection and pregnancy outcomes in intravenous drug users. JAMA. 1989;261(9): 1289–1294.

    Article  PubMed  CAS  Google Scholar 

  55. Minkoff H, Willoughby A, Mendez H. Serious infections during pregnancy among women with advanced human immunodeficiency virus infection. Am J Obstet Gynecol. 1990;162:30–34.

    PubMed  CAS  Google Scholar 

  56. Sperling R, Stratton P, O’Sullivan M. A survey of zidovudine use in pregnant women with human immunodeficiency virus infection. N Engl J Med. 1992;326:857–861.

    Article  PubMed  CAS  Google Scholar 

  57. Nanda D. Human immunodeficiency virus infection in pregnancy. Obstet Gynecol Clin North Am. 1990;17(3):617–626.

    PubMed  CAS  Google Scholar 

  58. Baskin CG, Law S, Wenger NK. Sulfadiazine rheumatic fever prophylaxis during pregnancy: does it increase the risk of kernicterus in the newborn? Cardiology. 1980;65:222–225.

    Article  PubMed  CAS  Google Scholar 

  59. Montgomery AB, Luce JM, Turner J, et al. Aerosolized pentamidine as sole therapy for Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. Lancet. 1987;1:480–482.

    Article  Google Scholar 

  60. Minkoff H. Care of pregnant women infected with human immunodeficiency virus. JAMA. 1987;258(19):2714–2712.

    Article  PubMed  CAS  Google Scholar 

  61. MacGregor S. Human immunodeficiency virus infection in pregnancy. Clin Perinatol. 1991; 18(l):33–50.

    PubMed  CAS  Google Scholar 

  62. MacDonald, Ginzburg H, Bolan J. HIV infection in pregnancy: epidemiology and clinical management. J Acq Immun Def Synd. 1991;4(2): 100–108.

    CAS  Google Scholar 

  63. Sprechers S, Soumenkoff G, Puissant F, et al. Vertical transmission of HIV in 15-week fetus (letter). Lancet. 1986;2:288.

    Article  Google Scholar 

  64. Rubinstein A, Bernstein L. The epidemiology of pediatric acquired immunodeficiency syndrome. Clin Immunol Immunopathol. 1986; 40:115–121.

    Article  PubMed  CAS  Google Scholar 

  65. Newell ML, Dunn D, Peckham CS, et al. Risk factors for mother to child transmission of HIV-1. Lancet. 1992;339:1007–1012.

    Article  Google Scholar 

  66. Blanche S, Rourioux C, Moscato ML, et al. A prospective study of infants born to women seropositive for human immunodeficiency virus type 1.N Engl J Med. 1989;320:1643–1648.

    Article  PubMed  CAS  Google Scholar 

  67. Lepage P, Van de Perre P, Caraal M. Transmission of HIV from mother to child. Lancet. 1987;2:400.

    Article  PubMed  CAS  Google Scholar 

  68. Colbunders RL, Kapita B, Nekwer W, et al. Breast-feeding and transmission of HIV. Lancet. 1988;2:1487.

    Article  Google Scholar 

  69. Logan S. Newell ML, Ades T, et al. Breastfeeding and HIV infection. Lancet. 1988; 1: 1346.

    Article  Google Scholar 

  70. Hira SK, Mangrola UG, Mwale C. Apparent vertical transmission of human immunodeficiency virus type 1 by breast feeding in Zambia. J Pediatr. 1990;117:421–430.

    Article  PubMed  CAS  Google Scholar 

  71. Mendez H, Jule J. Care of the infant born exposed to human immunodeficiency virus. Obstet Gynecol Clin North Am. 1990;17:637–649.

    PubMed  CAS  Google Scholar 

  72. Oxtoby MJ. Human immunodeficiency virus and other viruses in human milk: placing the issue in broader perspective. Pediatr J Infect Dis. 1988;7:825.

    CAS  Google Scholar 

  73. Minkoff H. Care of Pregnant women infected with human immunodeficiency Virus. JAMA. 1987;258:2714–2717.

    Article  PubMed  CAS  Google Scholar 

  74. Rogers M, Ou C, Rayfield M, et al. Use of the polymerase chain reaction for early detection of the proviral sequences of human immunodeficiency virus in infants born to seropositive mothers. N Engl J Med. 1989; 320:1649–1654.

    Article  PubMed  CAS  Google Scholar 

  75. Comeau AM, Harris JA, Mcintosh K. Polymerase chain reaction in detecting HIV infection among seropositive infants: relation to clinical status and age and to results of other assays. J Acq Immun Def Synd. 1992;5:27–278.

    Article  Google Scholar 

  76. Weiblen BJ, Lee FK, Cooper ER, et al. Early diagnosis of HIV infection in infants by detection of Ig A HIV antibodies. Lancet. 1990; 335:988–990.

    Article  PubMed  CAS  Google Scholar 

  77. Quinn T, Kline R, Halsey N, et al. Early diagnosis of perinatal HIV infection by detection of viral-specific Ig A antibodies. JAMA. 1991;266(24):3439–3442.

    Article  PubMed  CAS  Google Scholar 

  78. Seiff LB, Wright EC, Zimmerman HJ. Type B hepatitis after needlestick exposure: prevention with hepatitis B immunoglobulin: final report of the Veterans Administration cooperative study. Ann Intern Med. 1978;88:285–93.

    Google Scholar 

  79. McCray E. The cooperative needlestick surveillance group. Occupational risk of acquired immunodeficiency syndrome among health care workers. N Engl J Med. 314:1127–1132.

    Google Scholar 

  80. Hepatitis C in hospital employees with needlestick injuries. Ann Intern Med. 1991; 115:367–369.

    Google Scholar 

  81. Update: universal precautions for prevention of transmission of human immunodeficiency virus, hepatitis B virus and other blood-borne pathogens in health care settings. MMWR. 1988;37:377–388.

    Google Scholar 

  82. Henderson DK, Fahey BJ, Willy M, et al. Riskfor occupational transmission of human immunodeficiency virus type 1 (HIV-1) associated with clinical exposures: a prospective evaluation. Ann Intern Med. 1990;113:740–746.

    PubMed  CAS  Google Scholar 

  83. Recommendations for prevention of HIV transmission in health care settings. MMWR. 1987;36–25:15–185.

    Google Scholar 

  84. Department of Labor Occupational Safety and Health Administration. Occupational exposure to bloodborne pathogens. Federal Register. 1991;56:64175–64182.

    Google Scholar 

  85. Recommendations for preventing transmission of human immunodeficiency virus and hepatitis B virus to patients during exposure-prone invasive procedures. MMWR. 1991;40(RR-8): 1–9.

    Google Scholar 

  86. Centers for Disease Control. Possible transmission of human immunodeficiency virus to a patient during invasive dental procedure. MMWR. 1990;39:489–495.

    Google Scholar 

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Authors
  1. Patricia Herrera
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  2. J. Paul O’Keefe
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Editors and Affiliations

  1. Stritch School of Medicine, Loyola University of Chicago, Maywood, IL, 60153, USA

    John V. Knaus D.O. (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief) & John H. Isaacs M.D. (Professor of Obstetrics and Gynecology, Gynecologist-in-Chief) (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief) &  (Professor of Obstetrics and Gynecology, Gynecologist-in-Chief)

  2. Department of Obstetrics and Gynecologic, St. Francis Hospital, Evanston, IL, 60202, USA

    John V. Knaus D.O. (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief) (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief)

  3. Section of Gynecologic Oncology, St. Francis Hospital, Evanston, IL, 60202, USA

    John V. Knaus D.O. (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief) (Clinical Associate Professor of Obstetrics and Gynecology, Chairman, Chief)

  4. St. Francis Hospital, Evanston, IL, 60202, USA

    John H. Isaacs M.D. (Professor of Obstetrics and Gynecology, Gynecologist-in-Chief) (Professor of Obstetrics and Gynecology, Gynecologist-in-Chief)

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© 1993 Springer-Verlag New York, Inc.

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Herrera, P., O’Keefe, J.P. (1993). Human Immunodeficiency Virus (HIV) and Hepatitis. In: Knaus, J.V., Isaacs, J.H. (eds) Office Gynecology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4340-3_8

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  • DOI: https://doi.org/10.1007/978-1-4612-4340-3_8

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