Introduction: Understanding Blood Vessel Assembly in the Embryo
As we approach the end of the 1900s we are rediscovering the elegant embryology that flourished at the beginning of the century. Modern developmental biologists are beginning to place earlier embryological studies on a firm cellular and molecular basis. Sophisticated probes for specific molecules have stimulated a renaissance in the use of the light microscope. Fluorescent markers, digital image processing, and intravital labeling methods have had a major affect on understanding vascular morphogenesis. Targeted mutation of genes related to vascular development in mice bring the powerful tools of molecular biology to bear on understanding assembly of the vascular system. Recent progress is so rapid that keeping up with the latest discoveries is difficult.
KeywordsTIE2 Receptor Developmental Biologist Muscle Cell Precursor Arch Artery Cardiac Neural Crest
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