An Item Pool to Assess Activities of Daily Living in Alzheimer’s Disease
The evaluation of activities of daily living (ADL) is an underdeveloped area in clinical trials for Alzheimer’s Disease (AD). If an anti-dementia drug improves cognitive function or slows the rate of progression of AD, ideally this effect should extrapolate to a change in a patient’s ADL if it is clinically appreciable. Consequently, ADL assessment was identified as an important initiative by the Alzheimer’s Disease Cooperative Study (ADCS), a multi-center consortium formed to carry out clinical trials in AD.
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- Blessed G, Tomlinson BE, Roth M (1968): The association between quantitative measures of dementia and of senile changes in the cerebral grey matter of elderly subjects. Br J Psychol 225:797–811.Google Scholar
- Galasko D, Bennett D, Sano M et al., (1996): Development of a pool of items to assess activities of daily living in clinical trials for Alzheimer’s disease. Neurology 46:A248 (abstr).Google Scholar