Abstract
All areas of the cerebral cortex receive a dense cholinergic innervation which arises from the medial septal nucleus (Ch1), vertical and horizontal limb nuclei of the diagonal band (Ch2 and Ch3), and nucleus basalis of Meynert (nbM, Ch4). Neuroanatomical experiments in the monkey have shown that the hippocampal complex receives its cholinergic input predominantly from Ch1 and Ch2 whereas the cerebral neocortex and amygdala receive their cholinergic inputs predominantly from Ch4. The cholinergic innervation of the cerebral cortex constitutes a major component of the Ascending Reticular Activating System and plays an important role in a variety of behavioral realms, including memory, learning, arousal, and attention.
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© 1997 Birkhäuser Boston
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Smiley, J.F., Mesulam, MM. (1997). The Anatomy of Monoaminergic-Cholinergic Interactions in the Primate Basal Forebrain. In: Becker, R.E., Giacobini, E., Barton, J.M., Brown, M. (eds) Alzheimer Disease. Advances in Alzheimer Disease Therapy. Birkhäuser Boston. https://doi.org/10.1007/978-1-4612-4116-4_25
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DOI: https://doi.org/10.1007/978-1-4612-4116-4_25
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