The last two decades of the twentieth century have witnessed quantal advances in our knowledge of the biological processes that result in hearing. These have come about from the application of contemporary molecular biology, physiology, and imaging techniques that have been made available to all of biology in combination with discoveries in the domain of hearing. This volume, Clinical Aspects of Hearing, presents these pivotal developments as they are and will be applied to the understanding of normal and abnormal hearing in humans. The volume begins with information concerning the molecular genetics underlying hearing and hearing loss (Steel and Kimberling, Chapter 2). The flow of information proceeds to examine the relationship between auditory nerve regeneration and neurotropic factors (Van De Water, Staecker, Apfel, and Lefebvre, Chapter 3); auditory deprivation, which is an example of the effects of central nervous system (CNS) plasticity (Gravel and Ruben, Chapter 4); ototoxicity (Garetz and Schact, Chapter 5); viral infection and immune disease of the inner ear (Woolf, Chapter 6); otoacoustic emissions (Whitehead, Longsbury-Martin and McCoy, Chapter 7), and ends with information concerning tinnitus (Penner and Jastreboff, Chapter 8). The subjects covered in these seven chapters are products of the integration of knowledge of basic science and the morbidity found in clinical otology.
KeywordsInfluenza Polypeptide Dexamethasone Malaria Meningitis
Unable to display preview. Download preview PDF.
- Corwin JT (1986) Regeneration and self-repair in hair cell epithelia: Experimental capacities and limitations. In: Ruben RJ, Van De Water TR, Rubel EW (eds). The Biology of Change. Amsterdam: Excerpta Medica, pp 291–304.Google Scholar
- Feldman H (1970) A history of audiology: A comprehensive report and bibliography from the earliest beginnings to the present. Translation of the Beltone Institute for Hearing Research 22:1–109. Translation of Feldman H (1960) Die geschichtliche Entwicklung der Hörpüfungsmethoden, kurze Darstellung und Bibliographie vonder Anfängen bis zur Gegenwart. Zwanglose Abhandlugen aus dem Gebiet der Hals-Nasen-Ohren-Heilkunde. Leicher H, Mittermaier R, Theissing G. (Eds). Georg Thieme Verlag, Stuttgart.Google Scholar
- McCabe BF (1979) Autoimmune sensorineural hearing loss. Ann Oto Rhino Laryngol 88:585–589.Google Scholar
- Staecker H, et al. (1995B) The effects of neurotrophins on adult auditory neurons in vitro and in vivo. Abstracts of the Eighteenth Midwinter Meeting of the Association for Research in Otolaryngology, 705 p. 177.Google Scholar
- Zakon H (1986) Regeneration and recovery of function in the amphibian auditory system. In: Ruben RJ, Van De Water TR, Rubel EW (eds) The Biology of Change. Amsterdam: Excerpta Medica, pp 305–318.Google Scholar