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Transplantation of the Pancreas or Pancreatic Islet Cells

A Clinical Laboratory Perspective

  • Chapter
Clinical Pathology of Pancreatic Disorders

Part of the book series: Pathology and Laboratory Medicine ((PLM,volume 2))

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Abstract

Loss of the exocrine and endocrine pancreatic functions leaves the patient with serious digestive and metabolic problems. Causes of exocrine loss include cystic fibrosis, atrophic pancreatitis, chronic pancreatitis, infarction of the pancreas, surgical removal of the gland, atherosclerosis of the pancreas, pancreatic cysts, and other miscellaneous causes. More than about 85% of the acinar cells must be lost before abnormalities appear, indicating that the normal pancreas has tremendous exocrine reserves. Abdominal discomfort and abnormalities in digestion, including steatorrhea, weight loss, constipation or diarrhea, and flatulence, are typical findings.

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  1. John A. Lott
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  1. Department of Pathology, The Ohio State University, Columbus, OH, USA

    John A. Lott

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© 1997 Humana Press Inc.

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Lott, J.A. (1997). Transplantation of the Pancreas or Pancreatic Islet Cells. In: Lott, J.A. (eds) Clinical Pathology of Pancreatic Disorders. Pathology and Laboratory Medicine, vol 2. Humana Press. https://doi.org/10.1007/978-1-4612-3964-2_1

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  • DOI: https://doi.org/10.1007/978-1-4612-3964-2_1

  • Publisher Name: Humana Press

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