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The Evolution of Mammalian Platelets

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Thrombopoiesis and Thrombopoietins

Abstract

As described in detail in other chapters of this book, the mammalian platelet is derived from the cytoplasm of megakaryocytes, the only polyploid hemopoietic cell. Polyploid megakaryocytes and their progeny, nonnucleated platelets, are found only in mammals. In all other animal forms, cells involved in hemostasis and blood coagulation are nucleated. The nucleated cells primarily involved in nonmammalian hemostasis are designated thrombocytes to distinguish them from nonnucleated platelets.

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Authors
  1. Jack Levin
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Editor information

Editors and Affiliations

  1. The MGH Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA

    David J. Kuter MD, DPhil

  2. Amgen Inc., Thousand Oaks, California, USA

    Pamela Hunt PhD  & William Sheridan MD  & 

  3. Division of Hematology-Oncology, Department of Medicine, UCLA School of Medicine, Los Angeles, California, USA

    William Sheridan MD

  4. Department of Medicine, New York University Medical Center, New York, New York, USA

    Dorothea Zucker-Franklin MD

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© 1997 Humana Press Inc.

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Levin, J. (1997). The Evolution of Mammalian Platelets. In: Kuter, D.J., Hunt, P., Sheridan, W., Zucker-Franklin, D. (eds) Thrombopoiesis and Thrombopoietins. Humana Press. https://doi.org/10.1007/978-1-4612-3958-1_3

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  • DOI: https://doi.org/10.1007/978-1-4612-3958-1_3

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-8440-6

  • Online ISBN: 978-1-4612-3958-1

  • eBook Packages: Springer Book Archive

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