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Effect of Cytokines on the Development of Megakaryocytes and Platelets

An Ultrastructural Analysis

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Thrombopoiesis and Thrombopoietins

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Abstract

Megakaryocytes have intrigued investigators for more than a century, an interest spurred enormously by the availability of newer methods of analysis during the past 25 years. More recently, the discovery of hemopoietic cytokines culminating in the identification, purification, and manufacture of recombinant human thrombopoietins (rHuTPOs) has driven research on megakaryocytes and thrombocytopoiesis to an unprecedented level.

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Authors
  1. Dorothea Zucker-Franklin
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Editors and Affiliations

  1. The MGH Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA

    David J. Kuter MD, DPhil

  2. Amgen Inc., Thousand Oaks, California, USA

    Pamela Hunt PhD  & William Sheridan MD  & 

  3. Division of Hematology-Oncology, Department of Medicine, UCLA School of Medicine, Los Angeles, California, USA

    William Sheridan MD

  4. Department of Medicine, New York University Medical Center, New York, New York, USA

    Dorothea Zucker-Franklin MD

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© 1997 Humana Press Inc.

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Zucker-Franklin, D. (1997). Effect of Cytokines on the Development of Megakaryocytes and Platelets. In: Kuter, D.J., Hunt, P., Sheridan, W., Zucker-Franklin, D. (eds) Thrombopoiesis and Thrombopoietins. Humana Press. https://doi.org/10.1007/978-1-4612-3958-1_15

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  • DOI: https://doi.org/10.1007/978-1-4612-3958-1_15

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-8440-6

  • Online ISBN: 978-1-4612-3958-1

  • eBook Packages: Springer Book Archive

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