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Thyrotropin-Secreting Pituitary Tumors

Differential Diagnosis and Treatment

  • Chapter
Diseases of the Pituitary

Part of the book series: Contemporary Endocrinology ((COE,volume 3))

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Abstract

Thyroid stimulating hormone (TSH), or thyrotropin, is a glycoprotein normally secreted by the thyrotroph cells of the anterior pituitary gland. Like the other pituitary glycoproteins, TSH is composed of an alpha (α) and a beta (β) subunit. The α-subunit is identical among the glycoprotein hormones, whereas the unique TSH β-subunit confers biological specificity to the hormone. The TSH α and β subunits are glycosylated in specific patterns that determine subunit combination, clearance rates, and bioactivity.

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Authors
  1. Mary H. Samuels MD
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Editors and Affiliations

  1. University of Colorado Health Sciences Center, Denver, CO, USA

    Margaret E. Wierman MD

  2. Veterans Affairs Medical Center, Denver, CO, USA

    Margaret E. Wierman MD

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© 1997 Humana Press Inc.

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Samuels, M.H. (1997). Thyrotropin-Secreting Pituitary Tumors. In: Wierman, M.E. (eds) Diseases of the Pituitary. Contemporary Endocrinology, vol 3. Humana Press. https://doi.org/10.1007/978-1-4612-3954-3_15

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  • DOI: https://doi.org/10.1007/978-1-4612-3954-3_15

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-8438-3

  • Online ISBN: 978-1-4612-3954-3

  • eBook Packages: Springer Book Archive

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