Skip to main content
SpringerLink
Log in

Trans-1,2-Dichloroethylene

  • Chapter
Reviews of Environmental Contamination and Toxicology

Part of the book series: Reviews of Environmental Contamination and Toxicology ((RECT,volume 106))

  • 176 Accesses

Abstract

Trans-1,2-dichloroethylene, also known as 1,2-DCE, trans- 1,2-DCE, acetylene dichloride, and 1,2-dichloroethene, is used in a mixture with the cis-1,2-isomer as a captive intermediate in the production of other chlorinated solvents. Its structure and properties are shown in Table 1.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Albrecht P (1927) Arch Klin Chir 146:273. Cited in Clayton GD, Clayton FE (eds) Patty’s Industrial Hygienics and Toxicology, Vol 21. Wiley Interscience, NY. p 3545.

    Google Scholar 

  • ACGIH (1982) American Council of Government Industrial Hygienists. TLVs-Threshold limit values for chemical substances and physical agents in the workroom environment. ACGIH, Cincinnati, OH. p 15.

    Google Scholar 

  • Barnes DW, Sanders VM, White KL, Shopp GM, Munson AE (1985) Toxicology of trans-1,2-dichloroethylene in the mouse. Drug Chem Toxicol 8:373—392.

    Article  PubMed  CAS  Google Scholar 

  • Bonse G, Urban T, Montessano R, Tomatis L (1975) Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation. Biochem Pharmacol 24:1829–1834.

    Article  PubMed  CAS  Google Scholar 

  • Costa AK (1983) The chlorinated ethylenes: their hepatic metabolism and carcinogenicity. Diss Abst Int [B] 44(6):1797-B.

    Google Scholar 

  • Costa AK, Ivanetich KM (1982) The 1,2-dichloroethylenes: their metabolism by hepatic cytochrome P-450 in vitro. Biochem Pharmacol 31:2093–2102.

    Article  PubMed  CAS  Google Scholar 

  • Dobbs RA, Cohen JM (1980) Carbon absorption isotherms for toxic chemicals. Report no. EPA-600/3–80-023.a USEPA Office of Research and Development (ORD), Municipal Environmental Research Laboratory (MERL), Wastewater Treatment Division, Cincinnati, OH.

    Google Scholar 

  • Filser JG, Bolt HM (1979) Pharmacokinetics of halogenated ethylenes in rats. Arch Toxicol 42:123–136.

    Article  PubMed  CAS  Google Scholar 

  • Freundt JJ, Liebaldt GP, Lieberwirth E (1977) Toxicity studies on mws-l,2-dichloroethylene. Toxicology 7:141–153.

    Article  PubMed  CAS  Google Scholar 

  • Freundt JJ, Macholz J (1978) Inhibition of mixed function oxidases in rat liver by trans- and c/$-l,2-dichloroethylene. Toxicology 10:131–139.

    Article  PubMed  CAS  Google Scholar 

  • Galli A, Bauer C, Brenzetti G, Corsi C, Del Carratore R, Nieri R, Paolini M (1982a) (a) Studio in vitro. Attivita genetica dell’ 1,2-dichloroetilene. Boll Soc It Biol Sper 58: 860–863.

    CAS  Google Scholar 

  • Galli A, Bauer C, Brenzetti G, Corsi C, Del Carratore R, Nieri R, Paolini M (1982b) (a) Studio in vivo. Attivita genetica dell’ 1,2-dichloroetilene. Boll Soc It Biol Sper 58: 864–869.

    CAS  Google Scholar 

  • Greim H, Bonse G, Radwan Z, Reichert D, Henschler D (1975) Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxirane formation. Biochem Pharmacol 24:2013–2017.

    Article  PubMed  CAS  Google Scholar 

  • Hardie DWF (1964) Dichloroethylene. In: Mark HF, McKetta JJ Jr, Othmer DF (eds). Kirk-Othmer encyclopedia of chemical technology, 2nd Ed, Wiley-Interscience, New York, NY, vol 5. pp 178–183.

    Google Scholar 

  • Harkness JE, Agner JU (1983) The biology and medicine of rabbits and rodents. 2nd Ed, Lea and Fibiger, Philadelphia, PA. p 46.

    Google Scholar 

  • Hayes JR, Condie LW, Egle JL, Borzelleca JF (1987) The acute and subchronic toxicity in rats of ira/w-l,2-dichloroethylene in drinking water. J Am Coll Toxicol 6:471–478.

    CAS  Google Scholar 

  • Irish DD (1963) Vinylidene chloride. In: Patty FA (ed) Industrial hygiene and toxicology. 2nd Ed. Vol II. John Wiley and Sons, Inc., New York, NY. pp 1305–1309.

    Google Scholar 

  • Jaeger RJ, Shoner LG, Coffman LJ (1977) 1,2-Dichloroethylene hepatotoxicity: proposed mechanism of action of distribution and binding of 14C radioactivity following inhalation exposure in rats. Environ Hlth Perspect 21:113–119.

    CAS  Google Scholar 

  • Jenkins LJ Jr, Trabulus MJ, Murphy SD (1972) Biochemical effects of 1,1-dichloroethylene in rats: Comparison with carbon tetrachloride and 1,2-dichloroethylene. Toxicol Appl Pharmacol 23:501–510.

    Article  PubMed  CAS  Google Scholar 

  • Lehmann KB, Schmidt-Kehl L (1936) Study of the most important chlorohydrocarbons from the standpoint of industrial hygiene. Arch Hyg Bakteriol 116:131–268.

    Google Scholar 

  • Lentner C (1984) Geigy Scientific Tables. 8th Ed. Vol 3. Ciba-Geigy, Ltd., Basel, p 209.

    Google Scholar 

  • McKenna MJ, Zempel JA, Madrid EO, Gehring PJ (1978) The pharmacokinetics of [14C] vinylidene chloride in rats following inhalation exposure. Toxicol Appl Pharmacol 45:599–610.

    Article  PubMed  CAS  Google Scholar 

  • Munson AE, Saunders VM, Douglas KA, Sain LE, Kauffman BM, White KL Jr (1982) In vivo assessment of immunotoxicity. Environ Hlth Perspect 43:41–52.

    Article  CAS  Google Scholar 

  • Parsons F, Wood PR, DeMarco J (1984) Transformation of tetrachloroethene and trichloroethene in microcosms and groundwater. J Am Waterworks Assoc 76:56.

    CAS  Google Scholar 

  • Rampy LW, Quast JF, Humiston CG, Blamer MF, Schwetz BA (1977) Interim results of two-year toxicological studies in rats of vinylidene chloride incorporated in the drinking water or administered by repeated inhalation. Environ Hlth Perspect 21:33–43.

    Article  CAS  Google Scholar 

  • Torkelson TR and Rowe VK (1981) Halogenated aliphatic hydrocarbons. In: Clayton GD and Clayton FE (eds) Patty’s industrial hygiene and toxicology. 3rd Ed. Vol 2B. John Wiley and Sons, Inc., New York, NY. pp 3550–3553.

    Google Scholar 

  • USEPAa (1978) TSCA Inventory-non-confidential portion. USEPA Office of Toxic Substances, Washington, DC.

    Google Scholar 

  • USEPAa (1979) Water related environmental fate of 129 priority pollutants. Report no. EPA-440/4–79-029. USEPA Office of Water Planning and Standards, Washington, DC. December.

    Google Scholar 

  • USEPAa (1983) 1,2-Dichloroethylene occurrence in drinking water, food, and air. USEPA Office of Drinking Water (ODW), Washington, DC.

    Google Scholar 

  • USEPAa (1984a) Draft health effects criteria document for the dichloroethylenes. USEPA Criteria and Standards Division (CSD), Office of Drinking Water (ODW), Washington, DC. December.

    Google Scholar 

  • USEPAa (1984b) Method 502.1. Volatile halogenated organic compounds in water by purge and trap gas chromatography. USEPA Environmental Monitoring and Support Laboratory (EMSL), Cincinnati, OH. June.

    Google Scholar 

  • USEPAa (1985a) Method 524.1. Volatile halogenated organic compounds in water by purge and trap gas chromatography/mass spectrometry. USEPA Environmental Monitoring and Support Laboratory (EMSL), Cincinnati, OH. June.

    Google Scholar 

  • USEPAa (1985b) Office of Drinking Water Health Advisory program. Prepared by ICAIR, Life Systems, Inc. for the USEPA Office of Drinking Water (ODW), Criteria and Standards Division (CSD), Washington, DC.

    Google Scholar 

  • USEPAa (1985c) Draft technologies and costs for the removal of synthetic organic chemicals from potable water supplies. USEPA Science and Technology Branch, Criteria and Standards Division (CSD), Office of Drinking Water (ODW), Washington, DC.

    Google Scholar 

  • USEPA (1986) USEPA. Guidelines for carcinogen risk assessment. Fed Regis 51(185): 33992–34003.

    Google Scholar 

  • (USEPAa 1987) Trans-1,2-Dichloroethylene; Occurrence in food, water, and air. Office of Drinking Water, Washington, DC.

    Google Scholar 

  • Vogel TM, McCanty PL (1985) Biotransformation of tetrachloroethylene to trichloroethylene, dichlorethylene, vinyl chloride, and carbon dioxide under methanogenic conditions. Appl Environ Microbiol 49:1080–1083.

    PubMed  CAS  Google Scholar 

  • Windholz M, Budavari S, Stroumtsos LY, Fertig MN (eds) (1976) The Merck index-an encyclopedia of chemicals and drugs. 9th Ed. Merck & Co. Inc., Rahway, NJ.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. College of Agriculture, University of Arizona, 85721, Tuscon, Arizona, USA

    George W. Ware

Authors
  1. George W. Ware
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. College of Agriculture, University of Arizona, 85721, Tuscon, Arizona, USA

    George W. Ware

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer-Verlag New York Inc.

About this chapter

Cite this chapter

Ware, G.W. (1988). Trans-1,2-Dichloroethylene. In: Ware, G.W. (eds) Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology, vol 106. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3922-2_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-3922-2_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8402-4

  • Online ISBN: 978-1-4612-3922-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation